Results 101 to 110 of about 217,786 (288)

Curvature and torsion in growing actin networks

open access: yes, 2007
Intracellular pathogens such as Listeria monocytogenes and Rickettsia rickettsii move within a host cell by polymerizing a comet-tail of actin fibers that ultimately pushes the cell forward.
Daniel A Fletcher   +2 more
core   +1 more source

Light Activated Induction of Cuproptosis in Resistant Cancer Cells Using Polymeric BODIPY Nanoparticles for Photoactivated Chemotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This article presents a photo‐responsive nanoparticle platform that precisely triggers copper‐dependent cuproptotic cell death in (drug‐resistant) cancer cells. The system remains stable and inactive in the dark but releases cytotoxic species upon red‐light irradiation, achieving potent activity in drug‐resistant breast cancer cells.
Ricarda Zimmermann   +2 more
wiley   +1 more source

Biophysical Regulation of Cellular Function in Bone

open access: yes, 2022
Osteoporosis is the most prevalent bone disease and represents a major public health burden. Resulting from a reduction in bone quality and quantity, it can lead to fragility fractures with significant associated morbidity and mortality. Mechanical loading is a potent, albeit incompletely understood, anabolic stimulus that could lead to novel therapies
openaire   +2 more sources

The Molecular and Cellular Biophysics of Probiotic Bacteria [PDF]

open access: yesBiophysical Journal, 2015
Elie Metchnikoff proposed the use of probiotics a century ago. Probiotics regulate the integrity and functionality of gut microbiota. Currently, the scientific attention is more focused on the strain-specific features of probiotics and their use against pathogens or for the treatment of diseases and imbalances of the intestinal microbiota.
openaire   +1 more source

Microenvironmental Reprogramming by 3D Anisotropic Cardiac Extracellular Matrix Induces Nuclear Remodeling and Epigenetic Maturation of Chemically Induced Cardiomyocytes

open access: yesAdvanced Functional Materials, EarlyView.
A 3D anisotropic hydrogel derived from heart extracellular matrix guides cytoskeletal alignment and nuclear remodeling in reprogrammed cardiomyocyte‐like cells. This study reveals how matrix alignment modulates nuclear envelope dynamics and chromatin state, triggering transcriptional and functional maturation.
Seung Ju Seo   +7 more
wiley   +1 more source

Roughness of Transmembrane Helices Reduces Lipid Membrane Dynamics

open access: yesiScience, 2018
Summary: The dynamics of cellular membranes is primarily determined by lipid species forming a bilayer. Proteins are considered mainly as effector molecules of diverse cellular processes.
Marie Olšinová   +7 more
doaj   +1 more source

Modulating Iridium Electronic Structure With High‐Valent Metal Doping for Efficient and Durable Acidic Oxygen Evolution Reaction

open access: yesAdvanced Functional Materials, EarlyView.
We synthesized a novel IrCuOx/MnO2 heterostructure co‐doped with high‐valent W and Mo atoms, achieving exceptional acidic stability and high mass activity. Owing to the synergistic effects of structural and electronic modulation, cooperative charge redistribution occurs across both the interface and the lattice.
Minseo Kim   +17 more
wiley   +1 more source

Photo-Induced Depletion of Binding Sites in DNA-PAINT Microscopy

open access: yesMolecules, 2018
The limited photon budget of fluorescent dyes is the main limitation for localization precision in localization-based super-resolution microscopy. Points accumulation for imaging in nanoscale topography (PAINT)-based techniques use the reversible binding
Philipp Blumhardt   +6 more
doaj   +1 more source

Swelling‐Programmed Topographical Guidance for Dynamic Spheroid Self‐Assembly via a Mechanochemical Hydrogel Niche

open access: yesAdvanced Functional Materials, EarlyView.
A swelling‐programmed micropatterned hydrogel guides adherent cells through a controlled transition from cell–matrix anchoring to cadherin‐mediated cell–cell compaction, enabling rapid assembly of high‐viability spheroids with defined size and morphology.
Han Gyeol Nam   +8 more
wiley   +1 more source

A unified mechanistic model of niche, neutrality and violation of the competitive exclusion principle [PDF]

open access: yes, 2012
The origin of species richness is one of the most widely discussed questions in ecology. The absence of unified mechanistic model of competition makes difficult our deep understanding of this subject.
Lev V. Kalmykov, Vyacheslav L. Kalmykov
core   +1 more source

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