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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To compare the effectiveness of high‐efficacy treatments (HET) and low‐efficacy treatments (LET) in NMOSD patients with anti‐aquaporin‐4 antibodies (AQP4‐ab). Methods In this multi‐center study, we analyzed 183 AQP4‐ab seropositive NMOSD patients who received immunosuppressive treatments (IST).
Xiang Li +10 more
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Cellular Models of Trophoblast Differentiation [PDF]
Seminars in Reproductive Medicine, 2016 Orchestrated trophoblast differentiation is necessary to establish and maintain a normal pregnancy, however the molecular mechanisms that guide this process remain largely unknown. Although early studies of cytotrophoblast differentiation relied on animal models, more recent trophoblast research has involved in vitro models of human tissue.
Marissa L. Steinberg, Jared C. Robins
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Cellular features of differentiation in the nail
Microscopy Research and Technique, 1997Biochemical analysis indicated that the human nail plate contains two distinct types of keratin (skin-type and hair-type keratins), and several population of keratinocytes are thought to be associated with development of the nail. To elucidate the nature of the differentiation occurring in nail development, we examined the patterns of molecular markers
Hideoki Ogawa, Takashi Kitahara
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Embryogenesis and Cellular Differentiation
2018Embryonic development is a tightly regulated process that produces from a single zygote the some 400 different tissues and cell types forming the human body. The differentiation program of embryogenesis is under the control of transcription factor networks in the context of significant changes in the epigenetic landscape.
Ferdinand Molnár, Carsten Carlberg
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The effect of interferons on cellular differentiation
Blut, 1986The influence of IFN on cellular differentiation is well established in a variety of in vitro models such as Friend erythroleukemia, HL-60 cells or monocyte-macrophage differentiation. The exact effect of interferon, however, differs in special experimental situations.
Holger Kirchner, T. Moritz
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Cellular Differentiation and Morphogenesis
1988One of the major aims of this book is to appraise critically the role that PGRs play in plant development. Certain developmental phenomena which have been reported to be influenced by PGRs, such as juvenility, vernalization and the photoperiodic induction of flowering, involve the transition of shoot apices from one state of differentiation to another.
Richard Hooley, Jeremy A. Roberts
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Hypoxia, pseudohypoxia and cellular differentiation
Experimental Cell Research, 2017Tumor hypoxia correlates to aggressive disease, and while this is explained by a variety of factors, one clue to understand this phenomena was the finding that hypoxia induces a de-differentiated, stem cell-like phenotype in neuroblastoma and breast tumor cells. The hypoxia inducible transcription factors (HIFs) are regulated at the translational level
Caroline Wigerup +3 more
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Cellular neurothekeoma with histiocytic differentiation
Journal of Cutaneous Pathology, 2004Background: It is generally accepted that the two types of neurothekeoma (myxoid type and cellular type) represent the two poles of a spectrum. This concept, however, has recently been challenged, and cellular neurothekeomas have been suggested as a separate classification and are included in the ‘fibrohistiocytic’ category by some authors.
Yutaka Narisawa +2 more
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Rb and Cellular Differentiation
2007The pivotal role of the Retinoblastoma gene product pllO (pRb) in cellular differentiation has been postulated since the identification of pRb as a target of oncogenic events. The demonstration of the essential role of pRb during terminal differentiation of many tissues appeared evident along with the identification of the critical properties of pRb in
Lucia Latella, Pier Lorenzo Puri
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