Results 31 to 40 of about 1,459,173 (350)

Expression quantitative trait loci are highly sensitive to cellular differentiation state [PDF]

open access: yes, 2009
Blood cell development from multipotent hematopoietic stem cells to specialized blood cells is accompanied by drastic changes in gene expression for which the triggers remain mostly unknown.
A Gerrits   +48 more
core   +13 more sources

LncRNA HABON promoted liver cancer cells survival under hypoxia by inhibiting mPTP opening

open access: yesCell Death Discovery, 2022
Hypoxia is an important feature of the tumor microenvironment (TME). While targeting hypoxic TME is emerging as a potential strategy for treating solid tumors including liver cancer. Recent studies have shown that hypoxia can regulate tumor adaptation to
Lulu Wo   +9 more
doaj   +1 more source

Major transcriptome re-organisation and abrupt changes in signalling, cell cycle and chromatin regulation at neural differentiation in vivo [PDF]

open access: yes, 2014
Here, we exploit the spatial separation of temporal events of neural differentiation in the elongating chick body axis to provide the first analysis of transcriptome change in progressively more differentiated neural cell populations in vivo.
Abranches   +57 more
core   +4 more sources

Cellular differentiation in the leaf

open access: yesCurrent Opinion in Cell Biology, 1998
The past year has seen significant advances in our understanding of the mechanisms that regulate cellular differentiation in the leaf. It has been suggested that a common developmental pathway involving MYB-like transcription factors is responsible for distinguishing between cellular identities in the epidermis and that nuclear-cytoplasmic partitioning
openaire   +3 more sources

The circadian transcription factor ARNTL2 is regulated by weight-loss interventions in human white adipose tissue and inhibits adipogenesis

open access: yesCell Death Discovery, 2022
Misalignment of physiological circadian rhythms promotes obesity which is characterized by white adipose tissue (WAT) expansion. Differentiation of Adipose stem/progenitor cells (ASCs) contributes to WAT increase but the importance of the cellular clock ...
Markus Mandl   +14 more
doaj   +1 more source

Parallel analysis of tri-molecular biosynthesis with cell identity and function in single cells. [PDF]

open access: yes, 2019
Cellular products derived from the activity of DNA, RNA, and protein synthesis collectively control cell identity and function. Yet there is little information on how these three biosynthesis activities are coordinated during transient and sparse ...
Baskar, Reema   +3 more
core   +2 more sources

Cellular Acetylcholine Content and Neuronal Differentiation [PDF]

open access: bronzeJournal of Neurochemistry, 1997
Abstract: N18TG2 neuroblastoma clone is defective for biosynthetic neurotransmitter enzymes; its inability to establish functional synapses is overcome in the neuroblastoma × glioma 108CC15, where acetylcholine synthesis is also activated. These observations suggest a possible relation between the ability to produce acetylcholine and the capability to ...
F. Bignami   +6 more
openalex   +7 more sources

Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium [PDF]

open access: yes, 2017
Adaptive cellular responses are often required during wound repair. Following disruption of the intestinal epithelium, wound‐associated epithelial (WAE) cells form the initial barrier over the wound.
Lai, Chin-Wen   +7 more
core   +2 more sources

Blimp-1-dependent and -independent natural antibody production by B-1 and B-1-derived plasma cells. [PDF]

open access: yes, 2017
Natural antibodies contribute to tissue homeostasis and protect against infections. They are secreted constitutively without external antigenic stimulation.
Baumgarth, Nicole   +5 more
core   +1 more source

Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor beta 1 [PDF]

open access: yes, 2018
Chronic kidney disease (CKD) is common in geriatric cats, and the most prevalent pathology is chronic tubulointerstitial inflammation and fibrosis. The cell type predominantly responsible for the production of extra-cellular matrix in renal fibrosis is ...
A Clayton   +58 more
core   +1 more source

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