Cellular neurothekeoma with neuroendocrine differentiation
We report a case of cellular neurothekeoma with unusual clinicopathological features in which neuroendocrine markers, determined by immunohistochemistry were observed. Histologically, the tumor showed a micronodular architecture with hypercellular lobules composed of slightly spindled to epithelioid cells, with nuclear atypia or pleomorphism and ...
D'Antonio A. +4 more
openaire +6 more sources
LncRNA HABON promoted liver cancer cells survival under hypoxia by inhibiting mPTP opening
Hypoxia is an important feature of the tumor microenvironment (TME). While targeting hypoxic TME is emerging as a potential strategy for treating solid tumors including liver cancer. Recent studies have shown that hypoxia can regulate tumor adaptation to
Lulu Wo +9 more
doaj +1 more source
Patterns of cell movement within the Dictyostelium slug revealed by cell type-specific, surface labeling of living cells [PDF]
There are cells acattered in the rear, prespore region of the Dictyostelium slug that share many of the properties of the prestalk cells and that are therefore called anterior-like cells (ALCs).
Akiyama +41 more
core +1 more source
Misalignment of physiological circadian rhythms promotes obesity which is characterized by white adipose tissue (WAT) expansion. Differentiation of Adipose stem/progenitor cells (ASCs) contributes to WAT increase but the importance of the cellular clock ...
Markus Mandl +14 more
doaj +1 more source
Geometric control of myogenic cell fate. [PDF]
This work combines expertise in stem cell biology and bioengineering to define the system for geometric control of proliferation and differentiation of myogenic progenitor cells.
Conboy IM +9 more
core +3 more sources
Differential Cellular Gene Expression in Ganglioglioma [PDF]
Summary: Purpose: Gangliogliomas (GGs) are neuronal‐glial tumors highly associated with epilepsy. We hypothesized that the expression of select gene families including neurotransmitter receptor subunits and growth factors would be distinct in neurons and astrocytes within GG compared with adjacent cortex and that these changes would yield insights into
Samadani, Uzma +4 more
openaire +2 more sources
Role of FGFR2b expression and signaling in keratinocyte differentiation. Sequential involvement of PKCδ and PKCα [PDF]
The tumor suppressor epithelial isoform of the fibroblast growth factor receptor 2 (FGFR2b) induces human keratinocyte early differentiation. Moreover, protein kinases C (PKCs) are known to regulate the differentiation program in several cellular ...
Belleudi, Francesca +4 more
core +2 more sources
Cellular Acetylcholine Content and Neuronal Differentiation [PDF]
Abstract: N18TG2 neuroblastoma clone is defective for biosynthetic neurotransmitter enzymes; its inability to establish functional synapses is overcome in the neuroblastoma × glioma 108CC15, where acetylcholine synthesis is also activated. These observations suggest a possible relation between the ability to produce acetylcholine and the capability to ...
F. Bignami +6 more
openaire +5 more sources
An In Vitro Human Liver Model by iPSC-Derived Parenchymal and Non-parenchymal Cells
Summary: During liver development, hepatoblasts and liver non-parenchymal cells (NPCs) such as liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells (HSCs) constitute the liver bud where they proliferate and differentiate. Accordingly, we
Yuta Koui +7 more
doaj +1 more source
Physico-electrochemical Characterization of Pluripotent Stem Cells during Self-Renewal or Differentiation by a Multi-modal Monitoring System. [PDF]
Monitoring pluripotent stem cell behaviors (self-renewal and differentiation to specific lineages/phenotypes) is critical for a fundamental understanding of stem cell biology and their translational applications.
Horner, Christopher B +7 more
core +3 more sources

