Results 51 to 60 of about 4,342,740 (357)
An In Vitro Human Liver Model by iPSC-Derived Parenchymal and Non-parenchymal Cells
Stem Cell Reports, 2017 Summary: During liver development, hepatoblasts and liver non-parenchymal cells (NPCs) such as liver sinusoidal endothelial cells (LSECs) and hepatic stellate cells (HSCs) constitute the liver bud where they proliferate and differentiate. Accordingly, we
Yuta Koui +7 more
doaj +1 more source
Cellular metabolism regulates the differentiation and function of T-cell subsets
Cellular & Molecular ImmunologyT cells are an important component of adaptive immunity and protect the host from infectious diseases and cancers. However, uncontrolled T cell immunity may cause autoimmune disorders. In both situations, antigen-specific T cells undergo clonal expansion
Sicong Ma +3 more
semanticscholar +1 more source
Cellular Acetylcholine Content and Neuronal Differentiation [PDF]
Journal of Neurochemistry, 1997 Abstract: N18TG2 neuroblastoma clone is defective for biosynthetic neurotransmitter enzymes; its inability to establish functional synapses is overcome in the neuroblastoma × glioma 108CC15, where acetylcholine synthesis is also activated. These observations suggest a possible relation between the ability to produce acetylcholine and the capability to ...
F. Bignami +6 more
openaire +5 more sources
Scientific Reports, 2018 This study aimed to analyze the influence of the cellular differentiation, the tumor size and the underlying hepatic condition on the enhancement pattern of hepatocellular carcinoma (HCC) on contrast-enhanced ultrasound (CEUS).
Dan Yang +6 more
semanticscholar +1 more source
The transcription factor ATF5: role in cellular differentiation, stress responses, and cancer
OncoTarget, 2017 Activating transcription factor 5 (ATF5) is a cellular prosurvival transcription factor within the basic leucine zipper (bZip) family that is involved in cellular differentiation and promotes cellular adaptation to stress.
Thomas K. Sears, J. Angelastro
semanticscholar +1 more source
Recent development and gene therapy for glycogen storage disease type Ia
Liver Research, 2017 Glycogen storage disease type Ia (GSD-Ia) is an autosomal recessive metabolic disorder caused by a deficiency in glucose-6-phosphatase-α (G6Pase-α or G6PC) that is expressed primarily in the liver, kidney, and intestine. G6Pase-α catalyzes the hydrolysis
Janice Y. Chou +2 more
doaj +1 more source
Bone Marrow Failure as an Underrecognized Feature of KAT6A Syndrome
Pediatric Blood &Cancer, EarlyView.ABSTRACT KAT6A syndrome (Arboleda–Tham syndrome) is a rare disorder caused by heterozygous pathogenic variants in KAT6A, a histone acetyltransferase essential for chromatin remodeling and hematopoietic stem cell function. While neurodevelopmental features are well established, hematologic manifestations are underrecognized.
Ye Jee Shim +8 more
wiley +1 more source
Psychosocial Outcomes in Patients With Endocrine Tumor Syndromes: A Systematic Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Introduction The combination of disease manifestations, the familial burden, and varying penetrance of endocrine tumor syndromes (ETSs) is unique. This review aimed to portray and summarize available data on psychosocial outcomes in patients with ETSs and explore gaps and opportunities for future research and care.
Daniël Zwerus +6 more
wiley +1 more source
Molecular Genetics and Metabolism Reports, 2015 Glycogen storage disease type Ia (GSD-Ia), characterized by impaired glucose homeostasis and chronic risk of hepatocellular adenoma (HCA), is caused by a deficiency in glucose-6-phosphatase-α (G6Pase-α or G6PC) activity.
Young Mok Lee +4 more
doaj +1 more source
Mechano-Chemical Effect of Gelatin- and HA-Based Hydrogels on Human Retinal Progenitor Cells
Gels, 2023 Engineering matrices for cell therapy requires design criteria that include the ability of these materials to support, protect and enhance cellular behavior in vivo.
Pierre C. Dromel +5 more
doaj +1 more source