Results 81 to 90 of about 1,611,391 (358)

Proteomic analyses reveal misregulation of LIN28 expression and delayed timing of glial differentiation in human iPS cells with MECP2 loss-of-function. [PDF]

open access: yes, 2019
Rett syndrome (RTT) is a pervasive developmental disorder caused by mutations in MECP2. Complete loss of MECP2 function in males causes congenital encephalopathy, neurodevelopmental arrest, and early lethality.
Carromeu, Cassiano   +9 more
core   +2 more sources

Protein S-palmitoylation in cellular differentiation [PDF]

open access: yesBiochemical Society Transactions, 2017
Reversible protein S-palmitoylation confers spatiotemporal control of protein function by modulating protein stability, trafficking and activity, as well as protein–protein and membrane–protein associations. Enabled by technological advances, global studies revealed S-palmitoylation to be an important and pervasive posttranslational modification in ...
Zhang, Mingzi M., Hang, Howard C.
openaire   +2 more sources

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

open access: yesFEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii   +8 more
wiley   +1 more source

Cell-Type Specific Metabolic Flux Analysis: A Challenge for Metabolic Phenotyping and a Potential Solution in Plants

open access: yesMetabolites, 2017
Stable isotope labelling experiments are used routinely in metabolic flux analysis (MFA) to determine the metabolic phenotype of cells and tissues.
Merja T. Rossi   +4 more
doaj   +1 more source

Lineage dynamics of murine pancreatic development at single-cell resolution. [PDF]

open access: yes, 2018
Organogenesis requires the complex interactions of multiple cell lineages that coordinate their expansion, differentiation, and maturation over time.
Byrnes, Lauren E   +8 more
core   +2 more sources

Differentiable cellular automata

open access: yes, 2017
We describe a class of cellular automata (CAs) that are end-to-end differentiable. DCAs interpolate the behavior of ordinary CAs through rules that act on distributions of states. The gradient of a DCA with respect to its parameters can be computed with an iterative propagation scheme that uses previously-computed gradients and values.
openaire   +2 more sources

The role of fibroblast growth factors in cell and cancer metabolism

open access: yesFEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source

Dynamic shifts in chromatin states differentially mark the proliferative basal cells and terminally differentiated cells of the developing epidermis

open access: yesEpigenetics, 2020
Post-translational modifications on nucleosomal histones represent a key epigenetic regulatory mechanism to mediate the complex gene expression, DNA replication, and cell cycle changes that occur in embryonic cells undergoing lineage specification ...
Yan Ting Shue   +6 more
doaj   +1 more source

The Cord Weekly (January 12, 1968) [PDF]

open access: yes, 1968
Rab44 is an atypical Rab GTPase that contains some additional domains such as the EF-hand and coiled-coil domains as well as Rab-GTPase domain. Although Rab44 genes have been found in mammalian genomes, no studies concerning Rab44 have been reported yet.
山口, 優
core   +3 more sources

Control of cellular differentiation [PDF]

open access: yesNature, 1977
The Differentiation of Cells. By N. Maclean. Pp. iii + 216. (Edward Arnold: London, 1977.) Hardback £12; paperback £5.95.
openaire   +1 more source

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