Results 81 to 90 of about 4,741,341 (392)

Proliferation tracing with single-cell mass cytometry optimizes generation of stem cell memory-like T cells. [PDF]

, 2019
Selective differentiation of naive T cells into multipotent T cells is of great interest clinically for the generation of cell-based cancer immunotherapies. Cellular differentiation depends crucially on division state and time.
Bendall, Sean C, Borges, Luciene, Good, Zinaida, Nolan, Garry P, Sahaf, Bita, Samusik, Nikolay, Tibshirani, Robert, Vivanco Gonzalez, Nora   +7 more
core  

Pink1 and Parkin regulate Drosophila intestinal stem cell proliferation during stress and aging. [PDF]

, 2017
Intestinal stem cells (ISCs) maintain the midgut epithelium in Drosophila melanogaster Proper cellular turnover and tissue function rely on tightly regulated rates of ISC division and appropriate differentiation of daughter cells.
Abramov, Amcheslavsky, Amcheslavsky, Amcheslavsky, Benard, Biteau, Biteau, Biteau, Buchon, Buchon, Buchon, Christopher L. Koehler, Clark, Clarkson, Coppé, Correia-Melo, D. Leanne Jones, Deng, Greene, Guo, Guy A. Perkins, Hackenbrock, Han, Henchcliffe, Hochmuth, Hur, Jiang, Jiang, Jones, Kashatus, Lee, Lee, Li, Liu, Maeda, Marianes, Mark H. Ellisman, McGuire, Micchelli, Myant, Nakamura, Nicholson, Ohlstein, Ohlstein, Osterwalder, O’Brien, Park, Passos, Poole, Poole, Rana, Rera, Resende, Resnik-Docampo, Roman, Springer, Sykiotis, Takashima, Tian, Twig, Wang, Wang, Wei, Westermann, Yang, Youle, Zeng, Zeng, Zhu   +68 more
core   +1 more source

Epigenetic Control of Reprogramming and Cellular Differentiation [PDF]

Comparative and Functional Genomics, 2012
Recently, numerous interdisciplinary approaches that include integration of bioinformatics, epigenetics, and molecular and cellular biology have started to shed light on the complex dynamics that regulate cellular processes such as cell “stemness,” reprogramming, and differentiation.
Lucia Latella, Daniela Palacios, Sonia Forcales, Pier Lorenzo Puri   +3 more
openaire   +4 more sources

A stepwise emergence of evolution in the RNA world

FEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Oxygen gradients can determine epigenetic asymmetry and cellular differentiation via differential regulation of Tet activity in embryonic stem cells

Nucleic Acids Research, 2017
Graded levels of molecular oxygen (O2) exist within developing mammalian embryos and can differentially regulate cellular specification pathways. During differentiation, cells acquire distinct epigenetic landscapes, which determine their function ...
Simon Burr, A. Caldwell, Mei Chong, M. Beretta, Stephen Metcalf, M. Hancock, M. Arno, S. Balu, Valeria Leon Kropf, Rajesh K Mistry, A. Shah, G. Mann, A. Brewer   +12 more
semanticscholar   +1 more source

Phytocompounds and Regulation of Flavonoids in In Vitro-Grown Safflower Plant Tissue by Abiotic Elicitor CdCl₂

Metabolites
In this study, a Gas chromatography–mass spectrometry (GC–MS) investigation of embryogenic callus and somatic embryo regenerated shoots of Carthamus tinctorius revealed the presence of a variety of sugars, sugar acids, sugar alcohols, fatty acids ...
Bushra Ejaz, Abdul Mujib, Rukaya Syeed, Jyoti Mamgain, Moien Qadir Malik, Kanchan Birat, Yaser Hassan Dewir, Katalin Magyar-Tábori   +7 more
doaj   +1 more source

Role of the Mitochondrial Genome During Early Development in Mice [PDF]

, 1973
The role of the mitochondrial genome in early development and differentiation was studied in mouse embryos cultured in vitro from the two to four cell stage to the blastocyst (about 100 cells).
Chase, David G., Pikó, Lajos
core  

The Cord Weekly (January 12, 1968) [PDF]

, 1968
Rab44 is an atypical Rab GTPase that contains some additional domains such as the EF-hand and coiled-coil domains as well as Rab-GTPase domain. Although Rab44 genes have been found in mammalian genomes, no studies concerning Rab44 have been reported yet.
山口, 優
core   +3 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Auxin-Cytokinin Cross Talk in Somatic Embryogenesis of Coffea canephora

Plants, 2022
Cytokinins (CK) are plant growth regulators involved in multiple physiological processes in plants. One less studied aspect is CK homeostasis (HM). The primary genes related to HM are involved in biosynthesis (IPT), degradation (CKX), and signaling (ARR).
Johny R. Avilez-Montalvo, Ana O. Quintana-Escobar, Hugo A. Méndez-Hernández, Víctor Aguilar-Hernández, Ligia Brito-Argáez, Rosa M. Galaz-Ávalos, Miguel A. Uc-Chuc, Víctor M. Loyola-Vargas   +7 more
doaj   +1 more source