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In renal transplantation, BK-virus-associated nephropathy has emerged as a major complication, with a prevalence of 5–10% and graft loss in >50% of cases. BK-virus is a member of the Polyomavirus family and rarely induces apparent clinical disease in the
manon edekeyser+3 more
doaj +2 more sources
Science is constantly evolving and updated with current data on cell biology. The cellular aging phenomenon should be considered an evolutionary mechanism of the biological regulation of all living organisms. Factors initiating cellular aging are variable. Each cell type can respond differently to the activation factors of cellular aging.
M. M. Zhelavskyi+3 more
openaire +3 more sources
On the evolution of decoys in plant immune systems [PDF]
The Guard-Guardee model for plant immunity describes how resistance proteins (guards) in host cells monitor host target proteins (guardees) that are manipulated by pathogen effector proteins.
A Ashkenazi+12 more
core +2 more sources
The role of the immune response in the etiopathogenesis of endometriosis [PDF]
Endometriosis is a benign, chronic, estrogen-dependent condition, present in 10% of women of reproductive age. The condition is associated with chronic pelvic pain and infertility that influence their quality of life, as well as married life and has ...
Catalina Diana Stanica+3 more
doaj +1 more source
Vaccines elicit highly conserved cellular immunity to SARS-CoV-2 Omicron
The highly mutated SARS-CoV-2 Omicron (B.1.1.529) variant has been shown to evade a substantial fraction of neutralizing antibody responses elicited by current vaccines that encode the WA1/2020 spike protein1. Cellular immune responses, particularly CD8+
Jinyan Liu+12 more
semanticscholar +1 more source
The Robustness of Cellular Immunity Determines the Fate of SARS-CoV-2 Infection
Two years after the appearance of the SARS-CoV-2 virus, the causal agent of the current global pandemic, it is time to analyze the evolution of the immune protection that infection and vaccination provide.
E. Moga, Elionor Lynton-Pons, P. Domingo
semanticscholar +1 more source
The Interface of Tumour-Associated Macrophages with Dying Cancer Cells in Immuno-Oncology
Tumour-associated macrophages (TAMs) are essential players in the tumour microenvironment (TME) and modulate various pro-tumorigenic functions such as immunosuppression, angiogenesis, cancer cell proliferation, invasion and metastasis, along with ...
Isaure Vanmeerbeek+9 more
doaj +1 more source
An emerging SARS-CoV-2 mutant evading cellular immunity and increasing viral infectivity
During the current SARS-CoV-2 pandemic that is devastating the modern societies worldwide, many variants that naturally acquire multiple mutations have emerged.
Chihiro Motozono+23 more
semanticscholar +1 more source
Knowledge on the immunogenicity of vector‐based and mRNA‐vaccines in solid organ transplant recipients is limited. Therefore, SARS‐CoV‐2–specific T cells and antibodies were analyzed in 40 transplant recipients and 70 controls after homologous or ...
T. Schmidt+8 more
semanticscholar +1 more source
Humoral and cellular immunity to SARS‐CoV‐2 following COVID‐19 will likely contribute to protection from reinfection or severe disease. It is therefore important to characterise the initiation and persistence of adaptive immunity to SARS‐CoV‐2 amidst the
J. Sandberg+23 more
semanticscholar +1 more source