Results 21 to 30 of about 2,153,248 (300)

Necroptosis in Immuno-Oncology and Cancer Immunotherapy

Cells, 2020
Immune-checkpoint blockers (ICBs) have revolutionized oncology and firmly established the subfield of immuno-oncology. Despite this renaissance, a subset of cancer patients remain unresponsive to ICBs due to widespread immuno-resistance.
Jenny Sprooten, Pieter De Wijngaert, Isaure Vanmeerbeek, Shaun Martin, Peter Vangheluwe, Susan Schlenner, Dmitri V. Krysko, Jan B. Parys, Geert Bultynck, Peter Vandenabeele, Abhishek D. Garg   +10 more
doaj   +1 more source

Varying Cellular Immune Response against SARS-CoV-2 after the Booster Vaccination: A Cohort Study from Fukushima Vaccination Community Survey, Japan

Vaccines, 2023
Booster vaccination reduces the incidence of severe cases and mortality related to COVID-19, with cellular immunity playing an important role. However, little is known about the proportion of the population that has achieved cellular immunity after ...
Yuta Tani, Morihito Takita, Yurie Kobashi, Masatoshi Wakui, Tianchen Zhao, Chika Yamamoto, Hiroaki Saito, Moe Kawashima, Sota Sugiura, Yoshitaka Nishikawa, Fumiya Omata, Yuzo Shimazu, Takeshi Kawamura, Akira Sugiyama, Aya Nakayama, Yudai Kaneko, Tetsuhiko Kodama, Masahiro Kami, Masaharu Tsubokura   +18 more
doaj   +1 more source

Cellular Immunity in Aging

Journal of Investigative Dermatology, 1979
Our study of the aging process in human beings and in mice is complicated by our need to know whether we are observing diseases of aging or natural nondisease state processes. Results from studies on inbred strains of mice and retrospective studies on HLA types in aging human populations suggest that genetic effects play a significant role in ...
Yunis, Edmond J., Lane, M.A.
openaire   +2 more sources

Cochannel measurements for amplitude companded SSB voice communications [PDF]

, 1987
The authors examined certain aspects of a cellular radio system that are closely tied to the modulation method used, namely, channel sounding, interference immunity, signal quality, information transfer rate, and channel transparency.
A. Batman, A. Kanso, J.D. Marvill, Bateman, A, Kanso, A, McGeehan, JP, Marvill, JD, J.P. McGeehan   +7 more
core   +1 more source

A Conserved Tryptophan in the Envelope Cytoplasmic Tail Regulates HIV-1 Assembly and Spread

Viruses, 2022
The HIV-1 envelope (Env) is an essential determinant of viral infectivity, tropism and spread between T cells. Lentiviral Env contain an unusually long 150 amino acid cytoplasmic tail (EnvCT), but the function of the EnvCT and many conserved domains ...
Xenia Snetkov, Tafhima Haider, Dejan Mesner, Nicholas Groves, Schuyler B. van Engelenburg, Clare Jolly   +5 more
doaj   +1 more source

Lentiviral Hematopoietic Stem Cell Gene Therapy Rescues Clinical Phenotypes in a Murine Model of Pompe Disease

Molecular Therapy: Methods & Clinical Development, 2020
Pompe disease is a lysosomal storage disorder caused by malfunctions of the acid alpha-glucosidase (GAA) enzyme with a consequent toxic accumulation of glycogen in cells.
Giuseppa Piras, Claudia Montiel-Equihua, Yee-Ka Agnes Chan, Slawomir Wantuch, Daniel Stuckey, Derek Burke, Helen Prunty, Rahul Phadke, Darren Chambers, Armando Partida-Gaytan, Diego Leon-Rico, Neelam Panchal, Kathryn Whitmore, Miguel Calero, Sara Benedetti, Giorgia Santilli, Adrian J. Thrasher, H. Bobby Gaspar   +17 more
doaj   +1 more source

Curating the innate immunity interactome [PDF]

, 2010
peer-reviewedBackground: The innate immune response is the first line of defence against invading pathogens and is regulated by complex signalling and transcriptional networks.
Laird, Matthew R, Anastasia Sribnaia, Winsor, Geoffrey L., Lynn, David J, Giselle Ring, Foroushani, Amir K., Laird, Matthew R., Que, Jaimmie, Geoffrey L Winsor, Robert EW Hancock, Sribnaia, Anastasia, Hancock, Robert E.W., Ring, Giselle, Melissa Yau, Fiona SL Brinkman, Calvin Chan, Jaimmie Que, David J Lynn, Brinkman, Fiona S. L., Naseer, Misbah, Matthew R Laird, Yau, Melissa, Lo, Raymond, Raymond Lo, Chan, Calvin, Wee, Kathleen, Winsor, Geoffrey L, Breuer, Karin, Kathleen Wee, Amir K Foroushani, Hancock, R. E. W. (Robert E. W.), Brinkman, Fiona S., Misbah Naseer, Karin Breuer, Lynn, David J., Hancock, Robert E W, Foroushani, Amir K, Brinkman, Fiona S L   +37 more
core   +1 more source

Induction and in Vitro demonstration of cellular immunity to DNA and RNA viruses in guinea-pigs [PDF]

, 1975
Guinea-pigs were immunized with different cells infected with vaccinia virus, herpes simplex virus type 1, herpesvirus saimiri, and the virus of vesicular stomatitis. Development of cellular immunity against these viruses was observed with transformation
U. Koszinowski, Koszinowski, Ulrich H., G. Bandlow, Bandlow, G.   +3 more
core   +1 more source

Structural insights into the biological functions of the long pentraxin PTX3

Frontiers in Immunology, 2023
Soluble pattern recognition molecules (PRMs) are a heterogenous group of proteins that recognize pathogen- and danger-associated molecular patterns (PAMPs and DAMPs, respectively), and cooperate with cell-borne receptors in the orchestration of innate ...
Anna Margherita Massimino, Filippo Emanuele Colella, Barbara Bottazzi, Antonio Inforzato, Antonio Inforzato   +4 more
doaj   +1 more source

Correlation between COVID-19 cellular immunity test and IgG serology.

, 2023
Correlation between COVID-19 cellular immunity test and IgG serology.
Andréia Carolinne de Souza Brito (15188063), Vinicius da Cunha Lisboa (15188072), Thiago Thomáz Mafort (15188084), Mariana Soares da Cal (11767376), Wânia Ferraz Pereira Manfro (15188066), Marcelo Ribeiro-Alves (184765), Shayane Martins Rodrigues Gomes (15188060), Silvia Amaral Gonçalves da Silva (15188087), Luciana Silva Rodrigues (3074667), Roberto Stefan de Almeida Ribeiro (15188069), Leda dos Reis Castilho (15188078), Agnaldo José Lopes (9420944), Daniel Paiva Barros de Abreu (15188075), Patrícia Maria Lourenço Dutra (15188090), Luís Cristóvão de Moares Sobrino Porto (15188081)   +14 more
core   +1 more source