Results 11 to 20 of about 530,881 (263)

Association of systemic cellullar immunity with the development of cataract

open access: yesМедицинская иммунология, 2022
Among the causes of visual impairment, cataract occupies a significant proportion, which indicates a need for studying the causes of its development.
R. E. Osmanov, O. L. Fabrikantov
doaj   +1 more source

Characterization of the Bronchoalveolar Lavage Fluid by Single Cell Gene Expression Analysis in Healthy Dogs: A Promising Technique

open access: yesFrontiers in Immunology, 2020
Single-cell mRNA-sequencing (scRNA-seq) is a technique which enables unbiased, high throughput and high-resolution transcriptomic analysis of the heterogeneity of cells within a population.
Aline Fastrès   +6 more
doaj   +1 more source

Single cell dynamics of tumor specificity vs bystander activity in CD8+ T cells define the diverse immune landscapes in colorectal cancer

open access: yesCell Discovery, 2023
CD8+ T cell activation via immune checkpoint blockade (ICB) is successful in microsatellite instable (MSI) colorectal cancer (CRC) patients. By comparison, the success of immunotherapy against microsatellite stable (MSS) CRC is limited.
Daniel Morales Borràs   +21 more
doaj   +1 more source

Metabolic Inflammation and Cellular Immunity

open access: yesCells, 2023
Metabolic and immune cell responses are intimately linked and cross-regulated [...]
Sardar Sindhu, Rasheed Ahmad
doaj   +1 more source

The mediator of cellular immunity [PDF]

open access: yesCellular Immunology, 1973
Peritoneal exudates induced in rats infected with Listeria monocytogenes contain sensitized lymphocytes which can protect normal recipients against a Listeria challenge. The protective cells arise in lymphoid tissue remote from the peritoneal cavity. Those formed in the caudal lymph nodes of subcutaneously infected rats are delivered to the thoracic ...
D. D. McGregor, Pamela S. Logie
openaire   +2 more sources

Necroptosis in Immuno-Oncology and Cancer Immunotherapy

open access: yesCells, 2020
Immune-checkpoint blockers (ICBs) have revolutionized oncology and firmly established the subfield of immuno-oncology. Despite this renaissance, a subset of cancer patients remain unresponsive to ICBs due to widespread immuno-resistance.
Jenny Sprooten   +10 more
doaj   +1 more source

Varying Cellular Immune Response against SARS-CoV-2 after the Booster Vaccination: A Cohort Study from Fukushima Vaccination Community Survey, Japan

open access: yesVaccines, 2023
Booster vaccination reduces the incidence of severe cases and mortality related to COVID-19, with cellular immunity playing an important role. However, little is known about the proportion of the population that has achieved cellular immunity after ...
Yuta Tani   +18 more
doaj   +1 more source

Polyomavirus specific cellular immunity: from BK-virus-specific cellular immunity to BK-virus-associated nephropathy ?

open access: yesFrontiers in Immunology, 2015
In renal transplantation, BK-virus-associated nephropathy has emerged as a major complication, with a prevalence of 5–10% and graft loss in >50% of cases. BK-virus is a member of the Polyomavirus family and rarely induces apparent clinical disease in the
manon edekeyser   +3 more
doaj   +1 more source

Lentiviral Hematopoietic Stem Cell Gene Therapy Rescues Clinical Phenotypes in a Murine Model of Pompe Disease

open access: yesMolecular Therapy: Methods & Clinical Development, 2020
Pompe disease is a lysosomal storage disorder caused by malfunctions of the acid alpha-glucosidase (GAA) enzyme with a consequent toxic accumulation of glycogen in cells.
Giuseppa Piras   +17 more
doaj   +1 more source

A Conserved Tryptophan in the Envelope Cytoplasmic Tail Regulates HIV-1 Assembly and Spread

open access: yesViruses, 2022
The HIV-1 envelope (Env) is an essential determinant of viral infectivity, tropism and spread between T cells. Lentiviral Env contain an unusually long 150 amino acid cytoplasmic tail (EnvCT), but the function of the EnvCT and many conserved domains ...
Xenia Snetkov   +5 more
doaj   +1 more source

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