Results 241 to 250 of about 3,724,194 (363)

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

SARS-CoV-2-specific humoral and cellular immunity assessment in Peruvian vaccinated population: a cross-sectional study. [PDF]

PeerJ
Garcia-Paitan MY, Tapia-Rojas S, Alvarez Vega HS, Enciso-Benavides J, Pons MJ, Mayanga-Herrera A.   +5 more
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Longitudinal Evaluation of Humoral and Cellular Immunity After BNT162b2 COVID-19 Vaccination: Influence of Booster Type, Infection and Chronic Health Conditions. [PDF]

Vaccines (Basel)
Orlandi C, Conti I, Torre D, Barocci S, Magnani M, Stefanetti G, Casabianca A.   +6 more
europepmc   +1 more source

Replicating Rather than Nonreplicating Adenovirus-Human Immunodeficiency Virus Recombinant Vaccines Are Better at Eliciting Potent Cellular Immunity and Priming High-Titer Antibodies

, 2005
Bo Peng, Liqun Rejean Wang, Raúl Gómez Román, Alberta Davis‐Warren, David C. Montefiori, V. S. Kalyanaraman, David Venzon, Jun Zhao, Elaine Kan, Thomas J. Rowell, Krishna K. Murthy, Indresh K. Srivastava, Susan W. Barnett, Marjorie Robert-Guroff   +13 more
openalex   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Heterologous prime-boost Zika virus vaccination induces comprehensive humoral and cellular immunity in mouse models. [PDF]

Front Immunol
De Lorenzo G, Tandavanitj R, Preciado-Llanes L, Sanchez-Velazquez R, Prado Rocha R, Kim YC, Reyes-Sandoval A, Patel AH.   +7 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Age and primary vaccination schedule impact humoral and cellular immunity with an inactivated SARS-CoV-2 vaccine. [PDF]

iScience
Martínez-Balboa Y, Rodríguez-Guilarte L, Méndez C, Ríos M, Rivera DB, Moreno-Tapia D, Reyes HA, Pereira-Sánchez P, Orellana C, Cabrera A, Schultz BM, Duarte LF, Gálvez NMS, Melo-González F, Soto JA, Iturriaga C, Urzúa M, Navarrete MS, Rojas Á, Fasce RA, Fernández J, Mora J, Ramírez E, Weiskopf D, Grifoni A, Sette A, Zeng G, Meng W, CoronaVac03CL Study Group, Alvarez-Figueroa MJ, González-Aramundiz JV, Domínguez MA, González PA, Abarca K, Peñaloza HF, Bueno SM, Kalergis AM.   +36 more
europepmc   +1 more source

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source