Results 221 to 230 of about 2,153,248 (300)

Heterologous ORFV-Ad26 vaccination broadens antibody breadth and amplifies cellular immunity against SARS-CoV-2 spike. [PDF]

Front Immunol
Reguzova A, Haug V, Müller M, Fandrich M, Dulovic A, Amann R.   +5 more
europepmc   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Mannose and phenylboronate ester functionalized mesoporous silica nanoparticles contained in chitosan microneedles for enhancing cellular immunity and antitumor efficacy. [PDF]

Theranostics
Chen N, He Y, Zhang Y, Cui Y, Lu H, Zhang J, Zhang H, Zhao Q, Mao Y, Gao Y, Wang S.   +10 more
europepmc   +1 more source

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

Antibiotic-Induced Immunosuppression-A Focus on Cellular Immunity. [PDF]

Antibiotics (Basel)
Snow TAC, Singer M, Arulkumaran N, Arulkumaran N.   +3 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Longitudinal analysis of humoral and cellular immunity in SARS-CoV-2 exposed families. [PDF]

Sci Rep
Dulovic A, Rabsteyn A, Remppis J, Gentzcke IKE, Mueller J, Tuecks N, Becker M, Junker D, Kaiser PD, Traenkle B, Rothbauer U, Walz JS, Peter A, Hörber S, Ganzenmueller T, Iftner T, Stich M, Tönshoff B, Henneke P, Elling R, Debatin KM, Janda A, Schneiderhan-Marra N, Franz AR, Lang P, Renk H.   +25 more
europepmc   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

A booster dose of an inactivated SARS-CoV-2 vaccine targeting virus variants sustains protective humoral and cellular immunity. [PDF]

BMC Med
Méndez C, Rodríguez-Guilarte L, Palacios PA, Gutierrez-Vera C, Román F, Moreno-Tapia D, Ríos M, Reyes A, Cancino FA, Otero FF, Zurita C, Rivera D, Cabrera A, Duarte LF, Urzúa M, Iturriaga C, Rojas Á, Perez CM, Redlich AS, Fasce RA, Fernández J, Mora J, Ramírez E, Domínguez A, Weiskopf D, Grifoni A, Sette A, Zeng G, Meng W, Goldbatt D, Johnson M, CoronaVarCL study group, González-Aramundiz JV, Álvarez-Figueroa MJ, Abarca K, Carreño LJ, González PA, Kalergis AM, Peñaloza HF, Bueno SM.   +39 more
europepmc   +1 more source