Results 251 to 260 of about 870,585 (309)

Exosome Proteomics of SOD1D90A Mutation Suggest Early Disease Mechanisms, and FN1 as a Biomarker

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis (ALS) is a neuromuscular disease. Super oxide dismutase 1 (SOD1) gene mutations cause ALS, and the D90A mutation is associated with primarily upper motor neuron (UMN) loss. Objective Our goal is to reveal the early cellular events in ALS pathology and identify potential pharmacokinetic biomarkers, using well ...
Mukesh Gautam, Ali Laith, Aslihan Gunel, Melda Yilmaz, Nazli Basak, Halil Idrisoglu, P. Hande Ozdinler   +6 more
wiley   +1 more source

Decade-Long Sustained Cellular Immunity Induced by Sequential and Repeated Vaccination with Four Heterologous HIV Vaccines in Rhesus Macaques. [PDF]

Vaccines (Basel)
He X, Chen D, Ma Q, Hao Y, Li H, Zhang X, Cao Y, Feng X.   +7 more
europepmc   +1 more source

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann, Michelle M. Sonsalla, Cora Luzinski, Fernando Zacahua, David A. Harris, Dudley W. Lamming, Albee Messing   +6 more
wiley   +1 more source

Suppressive effects of deep balanced anesthesia on cellular immunity and protein expression: a randomized-controlled pilot study. [PDF]

BMC Anesthesiol
Nguyen XD, Horn A, Fischer D, Beck G, Spannenberger CC, Gaudilliere B, Horn JL, Thierse HJ, Frietsch T.   +8 more
europepmc   +1 more source

Study of the in vitro parasite specific cellular immune response during Trypanosoma Cruzi infection in mice

, 1987
Maria A. Curotto de Lafaille, Laura Cardellini Barbosa de Oliveira, Glória Maria Collet de Araújo Lima, Ises de Almeida Abrahamsohn   +3 more
openalex   +1 more source

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Chlorantraniliprole Enhances Cellular Immunity in Larvae of Spodoptera frugiperda (Smith) (Lepidoptera: Noctuidae). [PDF]

Insects
Liu Q, Deng X, Wang L, Xie W, Zhang H, Li Q, Yang Q, Jiang C.   +7 more
europepmc   +1 more source

MOLECULAR AND CELLULAR BASES OF THE IMMUNE REGULATION, IMMUNODIAGNOSTICS AND IMMUNOTHERAPHY (EXPEREMENTAL MODELS)

, 2014
Editorial article
openalex   +2 more sources

Elementary immunology [PDF]

, 2017
Gogolák, Péter, Koncz, Gábor
core