Results 31 to 40 of about 1,492,586 (335)

c-Src phosphorylation and activation of hexokinase promotes tumorigenesis and metastasis

Nature Communications, 2017
The protein tyrosine kinase c-Src is a renowned proto-oncogene with pleiotropic effects. Here, the authors show that c-Src induces the metabolic reprogramming of cancer cells by phosphorylating hexokinases HK1 and HK2, which in turns lead to increased HK
Jia Zhang, Suili Wang, Bin Jiang, Lihong Huang, Zhiliang Ji, Xiaotong Li, Huamin Zhou, Aidong Han, Ai Chen, Yanan Wu, Huanhuan Ma, Wentao Zhao, Qingwen Zhao, Changchuan Xie, Xiaoyan Sun, Yanming Zhou, Huiying Huang, Muhammad Suleman, Furong Lin, Lin Zhou, Fang Tian, Meijun Jin, Yana Cai, Nan Zhang, Qinxi Li   +24 more
doaj   +1 more source

Tolerogenic Dendritic Cells and T-Regulatory Cells at the Clinical Trials Crossroad for the Treatment of Autoimmune Disease; Emphasis on Type 1 Diabetes Therapy

Frontiers in Immunology, 2019
Tolerogenic dendritic cells and T-regulatory cells are two immune cell populations with the potential to prevent the onset of clinical stage type 1 diabetes, and manage the beginning of underlying autoimmunity, at the time-at-onset and onwards.
Brett Eugene Phillips, Yesica Garciafigueroa, Carl Engman, Massimo Trucco, Massimo Trucco, Nick Giannoukakis, Nick Giannoukakis   +6 more
doaj   +1 more source

Cellular neural network [PDF]

Scholarpedia, 2009
From the Publisher: The definitive reference for the world of Cellular Neural Networks (CNN). Demonstrates basic notions and possibilities using examples which include global optimization in a single transient, color halftoning and a CNN algorithm containing several cloning templates for detecting almost invisible defects in a textile pattern.
Giovanni Pazienza, Tamás Roska
openaire   +1 more source

Microbial synthesis of 4-hydroxybenzoic acid from renewable feedstocks

Food Chemistry: Molecular Sciences, 2021
4-Hydroxybenzoic acid (4HBA) and its esterified forms can be used as preservatives in the pharmaceutical and food industries. Here, we reported the establishment of a coenzyme-A (CoA) free multi-enzyme cascade in Escherichia coli to utilize biobased L ...
Yueyang Chen, Yufen Chen, Lijun Liu, Yang Zhang, Jifeng Yuan   +4 more
doaj   +1 more source

Engineering Saccharomyces cerevisiae‐based biosensors for copper detection

Microbial Biotechnology, 2022
Heavy metals, that is Cu(II), are harmful to the environment. There is an increasing demand to develop inexpensive detection methods for heavy metals.
Cong Fan, Danli Zhang, Qiwen Mo, Jifeng Yuan   +3 more
doaj   +1 more source

Outlines to Initiate Epilepsy Surgery in Low- and Middle-Income Countries

Journal of Integrative Neuroscience, 2022
Surgery is an essential treatment option for patients with drug-resistant epilepsy. While most epilepsy patients worldwide live in low- and middle-income countries (LMIC), most of these countries do not have epilepsy surgery, and those that do have ...
Peter Bäuerle, Ulf Schneider, Martin Holtkamp, Tengis Gloveli, Tamar Dugladze   +4 more
doaj   +1 more source

Data Offloading in Load Coupled Networks: A Utility Maximization Framework

, 2013
We provide a general framework for the problem of data offloading in a heterogeneous wireless network, where some demand of cellular users is served by a complementary network. The complementary network is either a small-cell network that shares the same
Ho, Chin Keong, Sun, Sumei, Yuan, Di
core   +2 more sources

Power Control and Channel Allocation for D2D Underlaid Cellular Networks [PDF]

, 2018
Device-to-Device (D2D) communications underlaying cellular networks is a viable network technology that can potentially increase spectral utilization and improve power efficiency for proximitybased wireless applications and services.
Abdallah, Asmaa, Chehab, Ali, Mansour, Mohammad M.   +2 more
core   +2 more sources

Cellular models for river networks [PDF]

Physical Review E, 2001
A cellular model introduced for the evolution of the fluvial landscape is revisited using extensive numerical and scaling analyses. The basic network shapes and their recurrence especially in the aggregation structure are then addressed. The roles of boundary and initial conditions are carefully analyzed as well as the key effect of quenched disorder ...
openaire   +5 more sources

Delayed diagnosis of POEMS syndrome, how AI tools can enhance diagnostic accuracy

European Journal of Case Reports in Internal Medicine
Polyneuropathy, organomegaly, endocrinopathy, monoclonal plasma cell disorder, and skin changes (POEMS) syndrome is a rare multisystem disorder often misdiagnosed due to its wide-ranging manifestations and clinical overlap with common medical conditions.
Max Jin, Sowbharnika Arivazhagan, Prerna Mewawalla, Santhosh Sadashiv, Arjun Lakshman   +4 more
doaj   +1 more source