Results 51 to 60 of about 777,473 (267)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Gut-associated IgA+ immune cells regulate obesity-related insulin resistance

open access: yesNature Communications, 2019
The effect of diet-induced obesity on intestinal B cell populations is not well understood despite emerging evidence of a critical role for the intestinal immune system in contributing to insulin resistance.
Helen Luck   +24 more
doaj   +1 more source

RF-EMF Exposure near 5G NR Small Cells

open access: yesSensors, 2023
Of particular interest within fifth generation (5G) cellular networks are the typical levels of radiofrequency (RF) electromagnetic fields (EMFs) emitted by ‘small cells’, low-power base stations, which are installed such that both workers and members of
Sam Aerts   +6 more
doaj   +1 more source

Deterministic Online Call Control in Cellular Networks and Triangle-Free Cellular Networks [PDF]

open access: yes, 2010
Wireless Communication Networks based on Frequency Division Multiplexing (FDM in short) plays an important role in the field of communications, in which each request can be satisfied by assigning a frequency. To avoid interference, each assigned frequency must be different to the neighboring assigned frequencies.
Lam, KC   +5 more
openaire   +3 more sources

Border Games in Cellular Networks [PDF]

open access: yesIEEE INFOCOM 2007 - 26th IEEE International Conference on Computer Communications, 2007
In each country today, cellular networks operate on carefully separated frequency bands. This careful separation is imposed by the regulators of the given country to avoid the interference between these networks. But, the separation is only valid for the network operators within the borders of their country, hence the operators are left on their own to
Márk Félegyházi   +3 more
openaire   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Nur77 suppresses hepatocellular carcinoma via switching glucose metabolism toward gluconeogenesis through attenuating phosphoenolpyruvate carboxykinase sumoylation

open access: yesNature Communications, 2017
Gluconeogenesis is downregulated in hepatocellular carcinoma. Here, the authors show that nuclear receptor Nur77 acts as a tumour suppressor sustaining gluconeogenesis by enhancing phosphoenolpyruvate carboxykinase (PEPCK1) stability via regulating its ...
Xue-li Bian   +14 more
doaj   +1 more source

Systematic CRISPR-Cas9-Mediated Modifications of Plasmodium yoelii ApiAP2 Genes Reveal Functional Insights into Parasite Development

open access: yesmBio, 2017
Malaria parasites have a complex life cycle with multiple developmental stages in mosquito and vertebrate hosts, and different developmental stages express unique sets of genes.
Cui Zhang   +10 more
doaj   +1 more source

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