Results 61 to 70 of about 8,616,473 (211)

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi, Maria Carmen Affinita, Giulia Fichera, Luisa Santoro, Angela Scagnellato, Calogero Virgone, Elena Poli, Gianni Bisogno   +7 more
wiley   +1 more source

The WNK-OXSR1 osmosensing pathway mediates intestinal regeneration via Hippo-YAP signaling

The EMBO Journal
Animals activate regenerative processes to repair injuries and restore homeostasis following tissue damage. A central question in regeneration is how damage signals are sensed and translated into regenerative growth.
Heming Cao, Xiawei Huang, Xiaobing Jiang, Jingrong Deng, Jiahui Wang, Chengfang Wu, Minhuang Hu, Bei Zeng, Zhihao Hu, Huimin Pan, Yuxia Yang, Kewei Zheng, Rui Shen, Mingqing Zhang, Bo Liu   +14 more
doaj   +1 more source

A global interaction network maps a wiring diagram of cellular function

Science, 2016
INTRODUCTION Genetic interactions occur when mutations in two or more genes combine to generate an unexpected phenotype. An extreme negative or synthetic lethal genetic interaction occurs when two mutations, neither lethal individually, combine to cause ...
M. Costanzo, Benjamin VanderSluis, Elizabeth N. Koch, A. Baryshnikova, Carles Pons, Guihong Tan, Wen Wang, Matej Ušaj, J. Hanchard, Susan D. Lee, V. Pelechano, Erin B. Styles, Maximilian Billmann, Jolanda van Leeuwen, Nydia van Dyk, Zhen‐Yuan Lin, Elena Kuzmin, J. Nelson, J. Piotrowski, Tharan Srikumar, S. Bahr, Yiqun Chen, R. Deshpande, Christoph F. Kurat, Sheena C. Li, Zhijian Li, M. M. Usaj, Hiroki Okada, N. Pascoe, Bryan-Joseph San Luis, Sara Sharifpoor, Emira Shuteriqi, Scott W. Simpkins, J. Snider, H. Suresh, Yizhao Tan, Hongwei Zhu, N. Malod-Dognin, Vuk Janjic, Natasa Przulj, O. Troyanskaya, I. Stagljar, T. Xia, Y. Ohya, A. Gingras, B. Raught, M. Boutros, L. Steinmetz, C. Moore, Adam P. Rosebrock, A. Caudy, C. Myers, B. Andrews, Charles Boone   +53 more
semanticscholar   +1 more source

Time to Diagnosis Among Children and Adolescents With Cancer in Québec, Canada: A Population‐Based Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely cancer diagnosis in children and adolescents is important to improving outcomes. We aimed to quantify time to diagnosis and assess variations by patient, demographic and system‐level factors. Procedure We conducted a population‐based study of individuals aged 0–19 years diagnosed with one of 12 cancers from 2010 to 2022 in ...
Callum Mullen, Ronald D. Barr, Erin Strumpf, Mariam El‐Zein, Eduardo L. Franco, Talía Malagón   +5 more
wiley   +1 more source

Impact of Japan's 2024 Physician Work‐Style Reform on Pediatric Hematology–Oncology: Educational Implications in a 2‐Year Survey

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Japan's 2024 physician work‐style reform introduced legally binding limits on physicians’ working hours, but its impact on education and workforce sustainability in pediatric hematology–oncology (PHO) remains unclear. Procedure We conducted a repeated cross‐sectional study with structured quantitative items and free‐text responses ...
Kiyohiko Kaizu, Masaharu Akiyama, Toshikazu Itabashi, Jun Hayakawa, Takahiro Kikuchi, Ryohei Fukunaga, Katsuyoshi Koh, Takahiro Ueda   +7 more
wiley   +1 more source

Reassessing Bone Marrow Aspirate and Trephine Biopsies in Staging for Paediatric and Young Adult Patients With Ewing Sarcoma and Rhabdomyosarcoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma (ES) and rhabdomyosarcoma (RMS) are aggressive malignancies in children and adolescents where metastases impact prognosis. 18F‐fluoro‐2‐deoxy‐d‐glucose positron emission tomography/computed tomography (FDG‐PET/CT) and bone marrow aspirate and trephine biopsies (BMAT) are used to identify disease involvement.
Imogen Andrews, Bruce Goodwin, Lauren Buckley, Rick Walker   +3 more
wiley   +1 more source

Traffic Prediction of Wireless Cellular Networks Based on Deep Transfer Learning and Cross-Domain Data

IEEE Access, 2020
Wireless cellular traffic prediction is a critical issue for researchers and practitioners in the 5G/B5G field. However, it is very challenging since the wireless cellular traffic usually show high nonlinearities and complex patterns.
Qingtian Zeng, Qiang Sun, Geng Chen, Hua Duan, Chao Li, Ge Song   +5 more
doaj   +1 more source

A Bibliometric Analysis of Publications in Uremic Toxins From 1991 to 2024

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Uremic toxins are a growing area of research in nephrology, with significant implications in the progression and treatment of chronic kidney disease (CKD) and the management of end‐stage kidney disease (ESKD). This bibliometric analysis aims to evaluate the global research trends, key contributors, and the impact of publications in ...
Yuh‐Shan Ho, Karim M. Soliman, Wisit Cheungpasitporn, Wannasit Wathanavasin, Ahmed Daoud, Ahmed I. Kamal, Balázs Szamosfalvi, Tibor Fülöp   +7 more
wiley   +1 more source

Coexistence and Performance Limits for the Cognitive Broadband Satellite System and mmWave Cellular Network

IEEE Access, 2020
The application of millimeter wave (mmWave) spectrum for the next generation broadband communications has received significant attention recently. In this work, we investigate the performance limits for the coexistence of the geo-stationary orbit (GEO ...
Qianfeng Zhang, Kang An, Xiaojuan Yan, Tao Liang   +3 more
doaj   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source