Results 61 to 70 of about 777,473 (267)

Understanding bufferbloat in cellular networks [PDF]

Proceedings of the 2012 ACM SIGCOMM workshop on Cellular networks: operations, challenges, and future design, 2012
Bufferbloat is a prevalent problem in the Internet where excessive buffers incur long latency, substantial jitter and sub-optimal throughput. This work provides the first elaborative understanding of bufferbloat in cellular networks. We carry out extensive measurements in the 3G/4G networks of the four major U.S.
Haiqing Jiang, Zeyu Liu, Yaogong Wang, Kyunghan Lee, Injong Rhee   +4 more
openaire   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

The WNK-OXSR1 osmosensing pathway mediates intestinal regeneration via Hippo-YAP signaling

The EMBO Journal
Animals activate regenerative processes to repair injuries and restore homeostasis following tissue damage. A central question in regeneration is how damage signals are sensed and translated into regenerative growth.
Heming Cao, Xiawei Huang, Xiaobing Jiang, Jingrong Deng, Jiahui Wang, Chengfang Wu, Minhuang Hu, Bei Zeng, Zhihao Hu, Huimin Pan, Yuxia Yang, Kewei Zheng, Rui Shen, Mingqing Zhang, Bo Liu   +14 more
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Traffic Prediction of Wireless Cellular Networks Based on Deep Transfer Learning and Cross-Domain Data

IEEE Access, 2020
Wireless cellular traffic prediction is a critical issue for researchers and practitioners in the 5G/B5G field. However, it is very challenging since the wireless cellular traffic usually show high nonlinearities and complex patterns.
Qingtian Zeng, Qiang Sun, Geng Chen, Hua Duan, Chao Li, Ge Song   +5 more
doaj   +1 more source

Localization performance in cellular networks [PDF]

2015 IEEE International Conference on Communication Workshop (ICCW), 2015
When the Global Positioning System is unavailable, cellular networks become the dominant vehicle for positioning. However, no tractable approach exists for gaining general insights into localization performance in such networks. Instead, analysis is often done using deterministic network models or with complex system-level simulations, resulting in ...
Javier Schloemann, Harpreet S. Dhillon, R. Michael Buehrer   +2 more
openaire   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Coexistence and Performance Limits for the Cognitive Broadband Satellite System and mmWave Cellular Network

IEEE Access, 2020
The application of millimeter wave (mmWave) spectrum for the next generation broadband communications has received significant attention recently. In this work, we investigate the performance limits for the coexistence of the geo-stationary orbit (GEO ...
Qianfeng Zhang, Kang An, Xiaojuan Yan, Tao Liang   +3 more
doaj   +1 more source