Results 41 to 50 of about 6,348,214 (302)

Revealing a Mutant-Induced Receptor Allosteric Mechanism for the Thyroid Hormone Resistance

iScience, 2019
Summary: Resistance to thyroid hormone (RTH) is a clinical disorder without specific and effective therapeutic strategy, partly due to the lack of structural mechanisms for the defective ligand binding by mutated thyroid hormone receptors (THRs).
Benqiang Yao, Yijuan Wei, Shuchi Zhang, Siyu Tian, Shuangshuang Xu, Rui Wang, Weili Zheng, Yong Li   +7 more
doaj   +1 more source

Engineering Saccharomyces cerevisiae‐based biosensors for copper detection

Microbial Biotechnology, 2022
Heavy metals, that is Cu(II), are harmful to the environment. There is an increasing demand to develop inexpensive detection methods for heavy metals.
Cong Fan, Danli Zhang, Qiwen Mo, Jifeng Yuan   +3 more
doaj   +1 more source

Brief Survey: Machine Learning in Handover Cellular Network

Engineering Proceedings, 2023
The proposed work offers a concise review of the application of machine learning (ML) to cellular network handovers (HO) via the Systematic Mapping Study (SMS) methodology, emphasizing the problem areas and requirements.
Viviana Párraga-Villamar, Pablo Lupera-Morillo, Felipe Grijalva, Henry Carvajal   +3 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Anti-PF4 ELISA-Negative, SRA-Positive Heparin-Induced Thrombocytopenia

Hematology Reports
Heparin products are frequently used in the inpatient setting to prevent and treat venous thromboembolism, but they simultaneously put patients at risk of developing heparin-induced thrombocytopenia (HIT). The 4Ts score determines the pretest probability
Abraham Attah, Chelsea Peterson, Max Jacobs, Rama Bhagavatula, Deep Shah, Robert Kaplan, Yazan Samhouri   +6 more
doaj   +1 more source

Solid Pseudopapillary Neoplasm of the Pancreas in Children and Adolescents: Expert Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Solid pseudopapillary neoplasm of the pancreas (SPN) is a rare low‐grade malignant exocrine pancreatic tumor, mostly discovered during the second decade of life in females, with a very good prognosis, provided microscopically complete surgical excision is achieved.
Sabine Irtan, Michael Abele, Calogero Virgone, Michaela Kuhlen, Ricardo Lopez‐Almarez, Tal Ben‐Ami, Ewa Bien, Maja Cesen, Malgorzata A. Krawczyk, Andrea Ferrari, Gianni Bisogno, Yves Reguerre, Dominik T. Schneider, Louise Galmiche, Jorg Fuchs, Sarah Braungart, Bilgehan Yalcin, Ines B. Brecht, Daniel Orbach   +18 more
wiley   +1 more source

On coupled oscillators networks for the cellular neural network [PDF]

1993 IEEE International Symposium on Circuits and Systems, 2002
The authors propose two types of coupled oscillator networks and investigate their steady states. One network has a two-dimensional honeycomb structure. The other network has a two-dimensional lattice structure. In the honeycomb circuit, three adjacent oscillators are coupled by one coupling resistor and it is considered that the voltages of three ...
Yoshifumi Nishio, Shinsaku Mori, Akio Ushida   +2 more
openaire   +2 more sources

Nonlinear rheology of cellular networks

Cells & Development, 2021
39 pages, 9 ...
Duclut, C., Paijmans, J., Inamdar, M., Modes, C., Jülicher, F.   +4 more
openaire   +5 more sources

Ovarian Sex Cord Stromal Tumors in Children and Adolescents—The European Standard Clinical Practice Recommendations

Pediatric Blood &Cancer, EarlyView.
ABSTRACT As part of the European Cooperative Study Group for Paediatric Rare Tumours initiative, we developed standard clinical practice guidelines for ovarian sex cord stromal tumors, based on comprehensive national and international cohort analyses, literature review, and a final expert consensus conference.
Dominik T. Schneider, Kris‐Ann Schultz, Nora Schnitzler, Michael Abele, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Ines B. Brecht, Maja Cesen, Andrea Ferrari, Michaela Kuhlen, Malgorzata A. Krawczyk, Ricardo Lopez‐Almaraz, Yves Reguerre, Calogero Virgone, Daniel Orbach   +15 more
wiley   +1 more source

Microarray and Biochemical Analysis of Lovastatin-induced Apoptosis of Squamous Cell Carcinomas

Neoplasia: An International Journal for Oncology Research, 2002
We recently identified 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, the rate-limiting enzyme of the mevalonate pathway, as a potential therapeutic target of the head and neck squamous cell carcinomas (HNSCC) and cervical carcinomas (CC ...
Jim Dimitroulakos, Wilson H. Marhin, Jason Tokunaga, Jonathan Irish, Patrick Gullane, Linda Z. Penn, Suzanne Kamel-Reid   +6 more
doaj   +1 more source