Results 21 to 30 of about 8,616,473 (211)

Effect of Densification on Cellular Network Performance With Bounded Pathloss Model [PDF]

IEEE Communications Letters, 2016
In this letter, we investigate how network densification influences the performance of downlink cellular network in terms of coverage probability (CP) and area spectral efficiency (ASE).
Junyu Liu, Min Sheng, Lei Liu, Jiandong Li   +3 more
semanticscholar   +1 more source

The Future of Islet Transplantation Is Now

Frontiers in Medicine, 2018
Milestones in the history of diabetes therapy include the discovery of insulin and successful methods of beta cell replacement including whole pancreas and islet cell transplantation options.
Rita Bottino, Rita Bottino, Rita Bottino, Michael F. Knoll, Carmela A. Knoll, Suzanne Bertera, Massimo M. Trucco, Massimo M. Trucco, Massimo M. Trucco   +8 more
doaj   +1 more source

A new ALK inhibitor overcomes resistance to first‐ and second‐generation inhibitors in NSCLC

EMBO Molecular Medicine, 2021
More than 60% of nonsmall cell lung cancer (NSCLC) patients show a positive response to the first ALK inhibitor, crizotinib, which has been used as the standard treatment for newly diagnosed patients with ALK rearrangement.
Yue Lu, Zhenzhen Fan, Su‐Jie Zhu, Xiaoxing Huang, Zhongji Zhuang, Yunzhan Li, Zhou Deng, Lei Gao, Xuehui Hong, Ting Zhang, Li Li, Xihuan Sun, Wei Huang, Jingfang Zhang, Yan Liu, Baoding Zhang, Jie Jiang, Fu Gui, Zheng Wang, Qiyuan Li, Siyang Song, Xin Huang, Qiao Wu, Lanfen Chen, Dawang Zhou, Jianming Zhang, Cai‐Hong Yun, Liang Chen, Xianming Deng   +28 more
doaj   +1 more source

RIP1 autophosphorylation is promoted by mitochondrial ROS and is essential for RIP3 recruitment into necrosome

Nature Communications, 2017
Mitochondrial reactive oxygen species (ROS) promote necroptosis and the receptor interacting protein 1 (RIP1) is a key player in this form of cell death.
Yingying Zhang, Sheng Sean Su, Shubo Zhao, Zhentao Yang, Chuan-Qi Zhong, Xin Chen, Qixu Cai, Zhang-Hua Yang, Deli Huang, Rui Wu, Jiahuai Han   +10 more
doaj   +1 more source

Adaptive Scheme for Caching YouTube Content in a Cellular Network: Machine Learning Approach

IEEE Access, 2017
Content caching at base stations is a promising solution to address the large demands for mobile data services over cellular networks. Content caching is a challenging problem as it requires predicting the future popularity of the content and the ...
S. Tanzil, William Hoiles, V. Krishnamurthy   +2 more
semanticscholar   +1 more source

c-Src phosphorylation and activation of hexokinase promotes tumorigenesis and metastasis

Nature Communications, 2017
The protein tyrosine kinase c-Src is a renowned proto-oncogene with pleiotropic effects. Here, the authors show that c-Src induces the metabolic reprogramming of cancer cells by phosphorylating hexokinases HK1 and HK2, which in turns lead to increased HK
Jia Zhang, Suili Wang, Bin Jiang, Lihong Huang, Zhiliang Ji, Xiaotong Li, Huamin Zhou, Aidong Han, Ai Chen, Yanan Wu, Huanhuan Ma, Wentao Zhao, Qingwen Zhao, Changchuan Xie, Xiaoyan Sun, Yanming Zhou, Huiying Huang, Muhammad Suleman, Furong Lin, Lin Zhou, Fang Tian, Meijun Jin, Yana Cai, Nan Zhang, Qinxi Li   +24 more
doaj   +1 more source

Tolerogenic Dendritic Cells and T-Regulatory Cells at the Clinical Trials Crossroad for the Treatment of Autoimmune Disease; Emphasis on Type 1 Diabetes Therapy

Frontiers in Immunology, 2019
Tolerogenic dendritic cells and T-regulatory cells are two immune cell populations with the potential to prevent the onset of clinical stage type 1 diabetes, and manage the beginning of underlying autoimmunity, at the time-at-onset and onwards.
Brett Eugene Phillips, Yesica Garciafigueroa, Carl Engman, Massimo Trucco, Massimo Trucco, Nick Giannoukakis, Nick Giannoukakis   +6 more
doaj   +1 more source

Structural Basis for PPARs Activation by The Dual PPARα/γ Agonist Sanguinarine: A Unique Mode of Ligand Recognition

Molecules, 2021
Peroxisome proliferator-activated receptors (PPARs) play crucial roles in glucose and lipid metabolism and inflammation. Sanguinarine is a natural product that is isolated from Sanguinaria Canadensis, a potential therapeutic agent for intervention in ...
Siyu Tian, Rui Wang, Shuming Chen, Jialing He, Weili Zheng, Yong Li   +5 more
doaj   +1 more source

Cellular Network Traffic Scheduling With Deep Reinforcement Learning

AAAI Conference on Artificial Intelligence, 2018
Modern mobile networks are facing unprecedented growth in demand due to a new class of traffic from Internet of Things (IoT) devices such as smart wearables and autonomous cars.
Sandeep P. Chinchali, Pan Hu, Tianshu Chu, Manu Sharma, M. Bansal, Rakesh Misra, M. Pavone, S. Katti   +7 more
semanticscholar   +1 more source

Research on a Fusion Scheme of Cellular Network and Wireless Sensor for Cyber Physical Social Systems

IEEE Access, 2018
The Internet of Things (IOT) is considered to be the third wave of the world information industry after the computer and the Internet. In order to realize the ubiquitous access to the IOT, the cellular network can only be fused with the wireless sensor ...
Aimin Yang, Xiao-Lei Yang, Jinhe Chang, Bin Bai, Fanbei Kong, Qing Ran   +5 more
semanticscholar   +1 more source