Results 151 to 160 of about 928,680 (341)

Transform-Based Multiresolution Decomposition for Unsupervised Learning and Data Clustering of Cellular Network Behavior

open access: yesIEEE Access
The growing complexity of cellular networks makes it harder for network operators to control and manage the system. To ease the management and automatically detect network problems, unsupervised techniques have been put to use. This work proposes a novel
Juan Cantizani-Estepa   +5 more
doaj   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Glioblastoma metabolomics: uncovering biomarkers for diagnosis, prognosis and targeted therapy

open access: yesJournal of Experimental & Clinical Cancer Research
Glioblastoma (GBM) is characterized by rapid growth, high molecular heterogeneity, and invasiveness. Specific aggressive factors are represented by MGMT promoter methylation, and IDH mutation status.
Susan Costantini   +8 more
doaj   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Active T1 transitions in cellular networks. [PDF]

open access: yesEur Phys J E Soft Matter, 2022
Duclut C   +4 more
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Inferring ligand-receptor cellular networks from bulk and spatial transcriptomic datasets with BulkSignalR. [PDF]

open access: yesNucleic Acids Res, 2023
Villemin JP   +9 more
europepmc   +1 more source

Optimising base station location for UMTS cellular networks

open access: diamond, 2014
G Kalata   +3 more
openalex   +1 more source

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