Results 171 to 180 of about 432,489 (267)

Powerful microscopy technologies decode spatially organized cellular networks that drive response to immunotherapy in humans. [PDF]

Curr Opin Immunol
Chen JH, Elmelech L, Tang AL, Hacohen N.
europepmc   +1 more source

Public Perception of the Fifth Generation of Cellular Networks (5G) on Social Media. [PDF]

Front Big Data, 2021
Dashtipour K, Taylor W, Ansari S, Gogate M, Zahid A, Sambo Y, Hussain A, Abbasi QH, Imran MA.   +8 more
europepmc   +1 more source

Slicing in Modern Cellular Networks [PDF]

Wireless Communications and Mobile Computing, 2019
Piotr Zwierzykowski, Pei Xiao 0001, Dejan Vukobratovic, Anna Zakrzewska   +3 more
openaire   +2 more sources

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

High aggressiveness of papillary thyroid cancer: from clinical evidence to regulatory cellular networks. [PDF]

Cell Death Discov
Zhang J, Xu S.
europepmc   +1 more source

Transcriptional landscape of cellular networks reveal interactions driving the dormancy mechanisms in cancer. [PDF]

Sci Rep, 2021
Uzuner D, Akkoç Y, Peker N, Pir P, Gözüaçık D, Çakır T.   +5 more
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Spatial multiplexed immunofluorescence analysis reveals coordinated cellular networks associated with overall survival in metastatic osteosarcoma. [PDF]

Bone Res
Lacinski RA, Dziadowicz SA, Melemai VK, Fitzpatrick B, Pisquiy JJ, Heim T, Lohse I, Schoedel KE, Llosa NJ, Weiss KR, Lindsey BA.   +10 more
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Location-Awareness for Failure Management in Cellular Networks: An Integrated Approach. [PDF]

Sensors (Basel), 2021
Fortes S, Baena C, Villegas J, Baena E, Asghar MZ, Asghar MZ, Barco R.   +6 more
europepmc   +1 more source