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Fermented Porcine Placenta and Its Dipeptides Modulate Cellular Senescence in Human Keratinocytes. [PDF]

open access: yesCurr Issues Mol Biol
Choi YJ   +9 more
europepmc   +1 more source
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Cellular senescence in glioma

Journal of Neuro-Oncology, 2023
Glioma is the most common primary brain tumor and is often associated with treatment resistance and poor prognosis. Standard treatment typically involves radiotherapy and temozolomide-based chemotherapy, both of which induce cellular senescence-a tumor suppression mechanism.Gliomas employ various mechanisms to bypass or escape senescence and remain in ...
RafaƂ, Chojak   +3 more
openaire   +2 more sources

Cellular Senescence

2015
The term senescence was coined more than 50 years ago to describe the loss of replicative capacity of normal human diploid cells in culture.1 At that time, senescence was proposed to generally reflect the process of cellular aging.2., 3. Early studies also noted differences between the propensity of normal and malignant cells to senesce, with malignant
Bolden, Jessica E., Lowe, Scott W.
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Phosphate and Cellular Senescence

2022
Cellular senescence is one type of permeant arrest of cell growth and one of increasingly recognized contributor to aging and age-associated disease. High phosphate and low Klotho individually and synergistically lead to age-related degeneration in multiple organs.
Ming Chang, Hu, Orson W, Moe
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Hypertension and cellular senescence

Biogerontology, 2023
Essential or primary hypertension is a wordwide health problem. Elevated blood pressure (BP) is closely associated not only with increased chronological aging but also with biological aging. There are various common pathways that play a role in cellular aging and BP regulation.
Baris, Afsar, Rengin Elsurer, Afsar
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Cellular senescence and neurodegeneration

Human Genetics, 2023
Advancing age is a major risk factor of Alzheimer's disease (AD). The worldwide prevalence of AD is approximately 50 million people, and this number is projected to increase substantially. The molecular mechanisms underlying the aging-associated susceptibility to cognitive impairment in AD are largely unknown.
Kristopher Holloway   +3 more
openaire   +2 more sources

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