Results 71 to 80 of about 1,861,365 (381)
Redox Biology, 2021 The soluble receptor for advanced glycation end-products (sRAGE) has been classically considered a sink for pro-inflammatory RAGE ligands and as such has been associated with protection from inflammatory stress and disease.
Jorge D. Erusalimsky
doaj
The tumor suppressor ING1 contributes to epigenetic control of cellular senescence [PDF]
, 2010 Cellular senescence is an effective tumor-suppressive mechanism that causes a stable proliferative arrest in cells with potentially oncogenic alterations.
Abad, María Alba +7 more
core +2 more sources
Lipids as Regulators of Cellular Senescence
Frontiers in Physiology, 2022 Lipids are key macromolecules that perform a multitude of biological functions ranging from maintaining structural integrity of membranes, energy storage, to signaling molecules.
Shruthi Hamsanathan, Aditi U. Gurkar
semanticscholar +1 more source
Downregulated miR-181a alleviates H2O2-induced oxidative stress and cellular senescence by targeting PDIA6 in human foreskin fibroblasts [PDF]
Anais Brasileiros de Dermatologia, 2023 Background Oxidative stress is strongly associated with cellular senescence. Numerous studies have indicated that microRNAs (miRNAs) play a critical part in cellular senescence.
Yan Huang +5 more
doaj +1 more source
Cellular senescence and aging: the role of B-MYB [PDF]
, 2014 Cellular senescence is a stable cell cycle arrest, caused by insults, such as: telomere erosion, oncogene activation, irradiation, DNA damage, oxidative stress, and viral infection.
Jat, PS, Lam, EW, Mowla, SN
core +1 more source
Role of p53 in the Regulation of Cellular Senescence
Biomolecules, 2020 The p53 transcription factor plays a critical role in cellular responses to stress. Its activation in response to DNA damage leads to cell growth arrest, allowing for DNA repair, or directs cellular senescence or apoptosis, thereby maintaining genome ...
M. Mijit +4 more
semanticscholar +1 more source
Cellular senescence and cardiovascular diseases: moving to the "heart" of the problem.
Physiological Reviews, 2022 Cardiovascular diseases (CVDs) constitute the prime cause of global mortality with an immense impact on patient quality of life and disability. Clinical evidence has revealed a strong connection between cellular senescence and worse cardiac outcomes in ...
K. Evangelou +6 more
semanticscholar +1 more source
Cellular senescence - its role in cancer and the response to ionizing radiation [PDF]
, 2011 © 2011 Sabin and Anderson; licensee BioMed Central Ltd. This article is available through the Brunel Open Access Publishing Fund. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http ...
Anderson, RM, Sabin, RJ
core +2 more sources
Cell Death and Disease, 2021 Emerging evidence suggests that cellular senescence induced by chemotherapy has been recognized as a new weapon for cancer therapy. This study aimed to research novel functions of B7-H3 in cellular senescence induced by a low dose of doxorubicin (DOX) in
Ruoqin Wang +9 more
doaj +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source