Results 21 to 30 of about 1,741,500 (304)
Colorectal cysts as a validating tool for CAR therapy
BMC Biotechnology, 2020 Background Treatment of cancers has largely benefited from the development of immunotherapy. In particular, Chimeric Antigen Receptor (CAR) redirected T cells have demonstrated impressive efficacy against B-cell malignancies and continuous efforts are ...
Pierre Dillard +7 more
doaj +1 more source
Turkish Journal of Hematology, 2022 Objective: Chimeric antigen receptor T (CAR-T) cell therapies have already made an impact on the treatment of B-cell malignancies. Although CAR-T cell therapies are promising, there are concerns about commercial products regarding their affordability and
Ebru Erdoğan +23 more
doaj +1 more source
Biological therapy in the treatment of melanoma [PDF]
, 2018 Melanoma is one of the most aggressive tumors and its incidence is on the rise. The low rates of survival in metastatic melanoma has led to the development of new drugs for this type of patient, such as biological therapy which has shown remarkable ...
Benea, Vasile +8 more
core +3 more sources
A TCR-based Chimeric Antigen Receptor
Scientific Reports, 2017 Effector T cells equipped with engineered antigen receptors specific for cancer targets have proven to be very efficient. Two methods have emerged: the Chimeric Antigen Receptors (CARs) and T-cell Receptor (TCR) redirection.
Even Walseng +8 more
doaj +1 more source
MiR-205-5p inhibition by locked nucleic acids impairs metastatic potential of breast cancer cells [PDF]
, 2018 Mir-205 plays an important role in epithelial biogenesis and in mammary gland development but its role in cancer still remains controversial depending on the specific cellular context and target genes.
De Cola A. +7 more
core +1 more source
Oncolytic herpes viruses, chemotherapeutics, and other cancer drugs [PDF]
, 2013 Oncolytic viruses are emerging as a potential new way of treating cancers. They are selectively replication-competent viruses that propagate only in actively dividing tumor cells but not in normal cells and, as a result, destroy the tumor cells by ...
Braidwood, L. +3 more
core +1 more source
Biomarkers of aging associated with past treatments in breast cancer survivors. [PDF]
, 2017 Radiation and chemotherapy are effective treatments for cancer, but are also toxic to healthy cells. Little is known about whether prior exposure to these treatments is related to markers of cellular aging years later in breast cancer survivors.
Bower, Julienne E +11 more
core +2 more sources
Lin28A induces energetic switching to glycolytic metabolism in human embryonic kidney cells [PDF]
, 2016 Background: Loss of a cell’s capacity to generate sufficient energy for cellular functions is a key hallmark of the ageing process and ultimately leads to a variety of important age-related pathologies such as cancer, Parkinson’s disease and ...
Docherty, Craig K. +2 more
core +3 more sources
Beyond the immune suppression: the immunotherapy in prostate cancer [PDF]
, 2015 Prostate cancer (PCa) is the second most common cancer in men.Aswell in many other human cancers, inflammation and immune suppression have an important role in their development.We briefly describe the host components that interact with the tumor to ...
Agliano', Anna Maria +4 more
core +3 more sources
HemaSphere, 2021 The nutritional status at diagnosis, as well as weight loss during chemotherapy, are important factors for morbidity and mortality in cancer patients. They might also influence outcomes in patients with acute myeloid leukemia (AML) receiving allogeneic ...
Dominic Brauer +7 more
doaj +1 more source