Results 261 to 270 of about 2,335,939 (309)
Some of the next articles are maybe not open access.
Cellular Uptake of Active Particles
Physical Review Letters, 2020Active particles are widely recognized to potentially revolutionize technologies in numerous biomedical applications. However, the physical origin behind cellular uptake of these particles in the nonequilibrium state remains scarcely understood. Here we combine Brownian dynamics simulation as well as theoretical analysis to provide the criterion for ...
Pengyu Chen +4 more
openaire +2 more sources
P53 and Cellular Glucose Uptake
Endocrine Research, 2012Tumor protein p53 is a transcription factor involved with cellular responses to stressors including limited glucose availability. We hypothesized that modulating p53 levels would affect cellular glucose uptake.Transfecting cultured primary mouse hepatocytes with p53 siRNA suppressed p53 mRNA expression >90%.
Alejandro J, de la Torre +2 more
openaire +2 more sources
Investigations on the cellular uptake of hexadecylphosphocholine
Lipids, 1993AbstractThe uptake of [(9,10)‐3H]hexadecylphosphocholine (HePC) in six tumor cell lines was studied. All cell lines incorporated HePC in similar amounts, with the exception of the epidermoid cancer cell line KB, which took up higher amounts of HePC. The uptake of HePC at 37°C was shown to be time and concentration dependent.
Fleer, E. +3 more
openaire +3 more sources
Cellular Uptake of Oligodeoxyribonucleoside Methylphosphonates
Antisense Research and Development, 1995The cellular uptake of oligodeoxyribonucleoside methylphosphonates has been evaluated using three radiolabeled oligomers. Oligomers I and II ([3H]-T8 and [3H]-T16, respectively) are nonionic methylphosphonate oligomers labeled with tritium on the phosphonate internucleotide linkage. EDA-III contains a single phosphodiester linkage, a [32P]-label and an
J T, Levis +3 more
openaire +2 more sources
Cellular Uptake of DNA Origami
2023This chapter discusses the methods involved in achieving and analyzing cellular uptake of DNA origami. While cells naturally internalize substances from their surroundings, more than a simple addition of DNA origami in the surrounding cell medium is necessary to ensure DNA origami particles successfully enter the intracellular environment.
openaire +2 more sources
Insights into Cellular Uptake of Nanoparticles
Current Drug Delivery, 2015Nanomaterials promise to improve disease diagnosis and treatment by enhancing the delivery of drugs, genes, biomolecules and imaging agents to specific subcellular targets. In order to optimize nanomaterial design for this purpose, a comprehensive understanding of how these materials are taken up and transported within the cell is required.
Morteza Hasanzadeh, Kafshgari +2 more
openaire +2 more sources
Understanding the cellular uptake of phosphopeptides
Cell Biochemistry and Biophysics, 1999Phosphopeptide-cellular uptake has been studied with a unique combination of tools designed to quantitate this phenomena and to understand properties that contribute to transmembrane penetration. High-affinity src-homology domain (SH2) hexapeptides for the phosphatidyl inositol 3-kinase system were used to judge cell penetration using red blood cells ...
A J, Allentoff +7 more
openaire +2 more sources
On the mechanism of cellular cadmium uptake
Biological Trace Element Research, 1989Review of the available evidence on the mechanism of cellular Cd uptake in the rat jejunum supports the concept that this process consists of nonspecific binding to anionic sites on the membrane, followed by a temperature-dependent and rate-limiting internalization step.
openaire +2 more sources
Nanoparticles: Cellular Uptake and Cytotoxicity
2014Understanding the interactions of nanoparticles (NPs) with cells and how these interactions influence their cellular uptake is essential to exploring the biomedical applications of NPs, particularly for drug delivery. Various factors, whether differences in physical properties of NPs or variations in cell-membrane characteristics, influence NP-cell ...
Isaac M, Adjei +2 more
openaire +2 more sources
CELLULAR UPTAKE OF COPPER BY HEPATOCYTES
Nutrition Reviews, 2009Selective accumulation of copper in isolated hepatocytes compared to fibroblasts is due in part to decreased copper efflux, perhaps the result of the presence of high-affinity intracellular copper-binding proteins. Preferential accumulation of copper by the liver may serve to protect extrahepatic tissues from copper toxicity.
openaire +2 more sources