Results 71 to 80 of about 918 (174)

4R-cembranoid confers neuroprotection against LPS-induced hippocampal inflammation in mice

open access: yesJournal of Neuroinflammation, 2021
Background Chronic brain inflammation has been implicated in the pathogenesis of various neurodegenerative diseases and disorders. For example, overexpression of pro-inflammatory cytokines has been associated with impairments in hippocampal-dependent ...
Luis A. Rojas-Colón   +7 more
doaj   +1 more source

Cubitanoids and Cembranoids from the Soft Coral Sinularia nanolobata [PDF]

open access: yesMarine Drugs, 2016
Two new cubitanoids, nanoculones A and B (1 and 2), and three new cembranoids, nanolobols A–C (3–5), as well as six known compounds, calyculone I (6), sinulariuol A (7), sinulariols C, D, H, and J (8–11), were isolated from the soft coral Sinularia nanolobata, collected off the coast of the eastern region of Taiwan.
Chih-Hua Chao   +6 more
openaire   +2 more sources

Cembranoids from the Vietnamese soft coral Sarcophyton ehrenbergi

open access: yesNatural Product Research, 2021
Using various chromatographic separations, two new cembranoids, ehrenbergols F and G (1 and 2), along with three known analogs ehrenbergol D (3), (+)-isosarcophine (4) and sinulariol Z2 (5) were isolated from the soft coral Sarcophyton ehrenbergi. The structural elucidation was done by extensive analysis of the 1 D and 2 D NMR, HR-ESI-QTOF-MS as well ...
Ngoc, Ninh Thi   +9 more
openaire   +2 more sources

Suppression of Migration and Invasion by 4‐Carbomethoxyl‐10‐Epigyrosanoldie E from the Cultured Soft Coral Sinularia sandensis through the MAPKs Pathway on Oral Cancer Cells

open access: yesAdvances in Pharmacological and Pharmaceutical Sciences, Volume 2024, Issue 1, 2024.
The primary reason for cancer‐related fatalities is metastasis. The compound 4‐carbomethoxyl‐10‐epigyrosanoldie E, derived from the Sinularia sandensis soft coral species grown in cultures, exhibits properties that counteract inflammation. Moreover, it has been observed to trigger both apoptosis and autophagy within cancerous cells.
Rou-Yi Fang   +7 more
wiley   +1 more source

An Improved Synthesis of 7, 8-Epoxy-1,3,11-cembratriene-15R(α), 16-diol, a Cembranoid of Marine Origin with a Potent Cancer Chemopreventive Activity

open access: yesMarine Drugs, 2004
An effective method for the synthesis of 7,8-epoxy-1,3,11-cembratriene-15R(α), 16-diol and its in vitro Epstein-Barr Virus Early Antigen (EBV-EA) Activation Chemopreventive Assay are reported.
Sherief I. Khalifa   +3 more
doaj   +1 more source

New Terpenes from the Egyptian Soft Coral Sarcophyton ehrenbergi

open access: yesMarine Drugs, 2014
Chemical investigations of the Egyptian soft coral Sarcophyton ehrenbergi have led to the isolation of compounds 1–3 as well as the previously reported marine cembranoid diterpene sarcophine (4).
Ahmed Elkhateeb   +6 more
doaj   +1 more source

Actions of octocoral and tobacco cembranoids on nicotinic receptors [PDF]

open access: yesToxicon, 2009
Nicotinic acetylcholine receptors (AChRs) are pentameric proteins that form agonist-gated cation channels through the plasma membrane. AChR agonists and antagonists are potential candidates for the treatment of neurodegenerative diseases. Cembranoids are naturally occurring diterpenoids that contain a 14-carbon ring.
Ferchmin, P. A.   +5 more
openaire   +3 more sources

Spectral data of nicotabaflavonoidglycoside

open access: yesData in Brief, 2018
The dataset addressed in this article relates to the research article entitled“Nicotabaflavonoidglycoside, the first example of cembranoid and flavonoid heterodimer from Nicotiana tabacum” (Yang et al., 2018) [1]. The dataset presents the MS4(879-571-421-
Cai-Yan Yang   +5 more
doaj   +1 more source

Semisynthetic and SAR Studies of Amide Derivatives of Neocrotocembraneic Acid as Potential Antitumor Agents

open access: yesMolecules, 2016
A series of novel amide derivatives of cembranoid neocrotocembraneic acid were designed and synthesized. The antiproliferative activities of these derivatives were evaluated against three human tumor cell lines (the human cervical cancer cell line HeLa ...
Hai Shang   +5 more
doaj   +1 more source

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