Synthesis and Evaluation of a 2,11‐Cembranoid‐Inspired Library [PDF]
AbstractThe 2,11‐cembranoid family of natural products has been used as inspiration for the synthesis of a structurally simplified, functionally diverse library of octahydroisobenzofuran‐based compounds designed to augment a typical medicinal chemistry library screen. Ring‐closing metathesis, lactonisation and SmI2‐mediated methods were exemplified and
Welford, AJ +11 more
openaire +3 more sources
Bioactive Cembranoids from the Soft Coral Genus Sinularia sp. in Borneo
Soft corals are known to be prolific producers of a wide spectrum of biologically active cembranoids. One new cembranoid, sinularolide F (2), along with three known compounds, cembranolide (1), (E,E,E)-6,10,14-trimethyl-3-methylene-cis-3α,4,5,8,9,12,13 ...
Takashi Kamada +5 more
doaj +1 more source
Bioassay-Guided Isolation of an Antibacterial Compound from the Indonesian Soft Coral
With the aim of searching for new antibacterial compound from marine soft corals, the investigation had been conducted on antibacterial activity of an extract from soft corals Sarcophyton trocheliophorum in the n-hexane, ethyl acetate, n-butanol, and ...
Masteria Yunovilsa Putra +4 more
doaj +1 more source
Numerosol A–D, New Cembranoid Diterpenes from the Soft Coral Sinularia numerosa
Four new cembrane-type diterpenes; numerosol A–D (1–4); along with a known steroid; gibberoketosterol (5); were isolated from the Taiwanese soft coral Sinularia numerosa.
Yen-Ju Tseng +3 more
doaj +1 more source
Computationally Assisted Structural Elucidation of Cembranoids from the Soft Coral Sarcophyton tortuosum [PDF]
Chih‐Hua Chao +6 more
openalex +1 more source
Lobophytones O–T, New Biscembranoids and Cembranoid from Soft Coral Lobophytum pauciflorum
Chemical examination of a Chinese soft coral Lobophytum pauciflorum resulted in the isolation of five new biscembranoids named lobophytones O–S (1–5) and a new “monomeric” cembrane lobophytone T (6). The structures of the new compounds were elucidated by
Wenhan Lin +4 more
doaj +1 more source
Anti-Inflammatory Cembranoids from the Soft Coral Lobophytum crassum [PDF]
Kuei-Hung Lai +5 more
openalex +1 more source
Feasibility of metabolomic analysis in assessing coral reefs environments.
This study aimed to explain the feasibility of fingerprint and chemical marker metabolomicanalysis in assessment of coral reefs environments. Based on literature review, both analysismight be implemented on coral reef environment assessment, with their ...
Hedi Indra Januar +2 more
doaj +1 more source
The effect of three oxylipin analogues, a terpenoid intermediate and wounding on the secondary metabolism of the soft corals Sarcophyton glaucum and Lobophyton pauciflorum was assessed. Examined oxylipins included prostaglandin (PG-E1), methyl jasmonate (
Mohamed A. Farag +4 more
doaj +1 more source
New Biscembranoids Sardigitolides A–D and Known Cembranoid-Related Compounds from Sarcophyton digitatum: Isolation, Structure Elucidation, and Bioactivities [PDF]
Tzu-Yin Huang +8 more
openalex +1 more source

