Three natural cembranoids from the Red Sea soft coral Sarcophyton glaucum namely sarcophine ( 1 ), (+)-7α,8β-dihydroxydeepoxysarcophine ( 2 ) and sarcophytolide ( 3 ) were evaluated for their potential inhibitory effects on growth of mouse melanoma B 16 ...
Pawel T. Szymanski +4 more
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Synthesis and stereochemistry of sarcophytol B: An anticancer cembranoid
Abstract A short (5 step), efficient synthesis of sarcophytol B (1) from farnesal is reported using a low-temperature, titanium-induced pinacol coupling reaction of 1,14-dialdehyde5 as the key step. An X-ray structure determination showed that sarcophytol B has trans diol stereochemistry.
John E. McMurry +2 more
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Cytotoxic Cembranoids from the Red Sea Soft Coral
One new cembrane diterpene, 2 R ,7 R ,8 R -dihydroxydeepoxysarcophine ( 1 ), together with three known compounds, 7α,8β-dihydroxy-deepoxysarcophine ( 2 ), 7β-acetoxy-8α-hydroxydeepoxysarcophine ( 3 ), and sarcophine ( 4 ), have been isolated from the Red
Mohamed-Elamir F. Hegazy +7 more
doaj +1 more source
The Soft Coral Sarcophyton trocheliophorum: A Warehouse of Terpenoids with Structural and Pharmacological Diversity. [PDF]
Yang QB, Wu Q, Chen JK, Liang LF.
europepmc +1 more source
A critical assessment of the Candida strains isolated from cigar tobacco leaves. [PDF]
Jia Y +7 more
europepmc +1 more source
Chemistry and bioactivity of secondary metabolites from South China Sea marine fauna and flora: recent research advances and perspective. [PDF]
Liu J, Gu YC, Su MZ, Guo YW.
europepmc +1 more source
Structural Modifications and Biological Activities of Natural α- and β-Cembrenediol: A Comprehensive Review. [PDF]
Xu K +6 more
europepmc +1 more source
New cembrane-type diterpenoids with anti-inflammatory activity from the South China Sea soft coral Sinularia sp. [PDF]
Du YQ +7 more
europepmc +1 more source
Mutation of the eunicellane synthase Bnd4 alters its product profile and expands its prenylation ability. [PDF]
Xu B, Ning W, Wei X, Rudolf JD.
europepmc +1 more source
Formulating Bioactive Terpenes. [PDF]
Lima ÁAN, Koester LS, Veiga-Junior VF.
europepmc +1 more source

