Results 51 to 60 of about 1,430 (181)

Potent Skin Cancer Chemopreventing Activity of Some Novel

open access: yesMarine Drugs, 2006
: In the course of our continuing research in development and evaluation of novel skin cancer chemopreventive agents from marine sources, five semi-synthetic cembranoids derived from the marine natural product sarcophine, isolated from the soft coral ...
Sherief Khalifa   +5 more
doaj   +1 more source

Modifications of Prenyl Side Chains in Natural Product Biosynthesis

open access: yesAngewandte Chemie, Volume 136, Issue 52, December 20, 2024.
This review summarizes the unique modifications of prenyl side chains involved in natural product biosynthesis, including epoxidation, dehydrogenation, oxidation of methyl groups to carboxyl groups, C−C bond cleavage and oxidative cyclization. Abstract In recent years, there has been a growing interest in understanding the enzymatic machinery ...
Huibin Wang, Yi Yang, Ikuro Abe
wiley   +2 more sources

New Terpenes from the Egyptian Soft Coral Sarcophyton ehrenbergi

open access: yesMarine Drugs, 2014
Chemical investigations of the Egyptian soft coral Sarcophyton ehrenbergi have led to the isolation of compounds 1–3 as well as the previously reported marine cembranoid diterpene sarcophine (4).
Ahmed Elkhateeb   +6 more
doaj   +1 more source

How do freshwater fish sperm find the egg? The physicochemical factors guiding the gamete encounters of externally fertilizing freshwater fish

open access: yesReviews in Aquaculture, Volume 12, Issue 2, Page 1165-1192, May 2020., 2020
Abstract The lifespan of spermatozoa from externally fertilizing freshwater fish ranges from a few seconds to several minutes, depending on the species. External factors, such as temperature, background flows and ion composition, play an important role in fertilization success.
Vitaliy Kholodnyy   +3 more
wiley   +1 more source

Cytotoxic Effects of Sarcophyton sp. Soft Corals—Is There a Correlation to Their NMR Fingerprints?

open access: yesMarine Drugs, 2017
Sarcophyton sp. soft corals are rich in cembranoid diterpenes, which represent the main chemical defense of corals against their natural predators in addition to their myriad biological effects in humans. Quantitative NMR (qNMR) was applied for assessing
Mohamed A. Farag   +8 more
doaj   +1 more source

Three New Cembranoids from the Taiwanese Soft Coral <em>Sarcophyton ehrenbergi</em>

open access: yesMarine Drugs, 2012
In order to search for new bioactive substances from marine organisms, we have investigated the acetone extracts of the soft coral <em>Sarcophyton ehrenbergi</em><em> </em>collected at San-Hsian-Tai, Taitong County, Taiwan ...
Shang-Kwei Wang   +2 more
doaj   +1 more source

Exploring the catalytic cascade of cembranoid biosynthesis by combination of genetic engineering and molecular simulations

open access: yesComputational and Structural Biotechnology Journal, 2020
While chemical steps involved in bioactive cembranoid biosynthesis have been examined, the corresponding enzymatic mechanisms leading to their formation remain elusive.
Patrick Schrepfer   +5 more
doaj   +1 more source

Biocatalytic and antimetastatic studies of the marine cembranoids sarcophine and 2-epi-16-deoxysarcophine [PDF]

open access: yes, 2006
The soft coral Sarcophyton glaucum is a rich resource of several bioactive cembranoids. Sarcophytol A (1) and sarcophine (2) are cembranoid diterpenes reported from this soft coral and extensively investigated for their cancer chemopreventive properties.
El Sayed, Khalid A.   +5 more
core   +2 more sources

Comprehensive study on the effects of various stressors on soft corals and zooxanthellae [PDF]

open access: yes, 2023
Soft corals have a remarkable potential as producer of secondary metabolites. However, they are vulnerable to changes in environment. Coral produce secondary metabolites as chemical defense against predators and environmental changes. In this thesis, the
Rahaweman, Ayu Christien
core   +1 more source

A brief review on new naturally occurring cembranoid diterpene derivatives from the soft corals of the genera Sarcophyton, Sinularia, and Lobophytum since 2016 [PDF]

open access: yes, 2019
This work reviews the new isolated cembranoid derivatives from species of the genera Sarcophyton, Sinularia, and Lobophytum as well as their biological properties, during 2016⁻2018.
Miguel, Maria   +2 more
core   +1 more source

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