Results 131 to 140 of about 25,204 (254)
Meta-analysis of genetic variants associated with human exceptional longevity [PDF]
, 2013 Despite evidence from family studies that there is a strong genetic influence upon exceptional longevity, relatively few genetic variants have been associated with this trait.
Andersen, Stacy L. +10 more
core +2 more sources
A Pilot Study on Prostate Cancer Risk and Pro-Inflammatory Genotypes: Pathophysiology and Therapeutic Implications [PDF]
, 2010 Host genetic factors are crucial risk determinants for many human cancers. In this framework, an interesting model is represented by prostate cancer (PC), which is featured by a complex pathophysiology with a strong genetic component. Multiple genes seem
Balistreri, C. +8 more
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This reflexion is published in memory of Väinö Kannisto, who died unexpectedly on 16 February 2002.
James W. Vaupel
core
The signature of longevity in Sicily [PDF]
, 2018 Ageing is a natural and physiological condition that is the result of compromised stress response, homeostatic imbalance and increased risk of developing diseases.
Accardi, G +10 more
core
Functional capacity and level of physical activity in centenarians of Florianópolis, Brazil
Revista da Educação Física, 2016 Aim: To compare the level of physical activity and functional capacity of centenarians from Florianópolis, Brazil. Methods: To measure the level of physical activity and functional capacity, pedometer and the Katz scale, respectively, were used.
Inês Amanda Streit +3 more
doaj
Lipid profile in elderly and centenarian subjects in Kazakhstan: a case-control study
Central Asian Journal of Medical Hypotheses and EthicsIntroduction. The health of centenarians is a major focus in global studies. Dyslipidemia is directly linked to the risk of cardiovascular diseases, which pose a growing burden on healthcare due to the increasing elderly population.
Yu. Ganzhula +4 more
doaj +1 more source
The ‘autoimmunome’ of centenarians
Journal of Translational AutoimmunityObjective: To identify signature proteins potentially linked to resistance to autoimmunity in the blood of centenarians. Methods: We conducted in silico data mining of previously published proteomic results using the Search Tool for the Retrieval of ...
Pedro Carrera-Bastos +10 more
doaj +1 more source
Age-dependent dynamics of screening metabolic parameters in long-livers and its biophysical estimation [PDF]
Саратовский научно-медицинский журнал, 2015 The purpose of the study: to examine age-dependent dynamics of parameters of biochemical screening in long-livers. Material and methods. The study included 201 long-livers divided (Saratov) into two groups: the main group (centenarians) and the control ...
Denisova Т.Р. +2 more
doaj
npj Biofilms and MicrobiomesThe gut microbiota of centenarians plays a vital role in promoting healthy longevity. We performed a cross-sectional study of 224 people from Jiaoling, China, which is globally recognised for the longevity of its residents.
Lei Wu +22 more
doaj +1 more source
Paraoxonase Activity and Genotype Predispose to Successful Aging [PDF]
, 2017 The paraoxonase 1 codon 192 R allele has been previously reported to have a role in successful aging. The relationship between PON1 genotypes, enzymatic activity, and mass concentration was evaluated in a group of 229 participants from 22 to 104 years of
Boemi, Massimo +9 more
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