Results 111 to 120 of about 25,204 (254)
BMC Genomics, 2007 Background Studies on heteroplasmy occurring in the mitochondrial DNA (mtDNA) control region (CR) in leukocytes of centenarians and younger subjects have shown that the C150T somatic transition is over-represented in centenarians.
Maletta Raffaele +11 more
doaj +1 more source
HLA and KIR Frequencies in Sicilian Centenarians [PDF]
, 2010 Several studies suggest that human longevity appears to be linked inextricably with optimal functioning of the immune system, suggesting that specific genetic determinants may reside in loci that regulate the immune response, as human leukocyte antigen
CANDORE, Giuseppina +5 more
core +1 more source
Differential Gene Expression in Human Hippocampus With Aging
Aging Cell, Volume 25, Issue 4, April 2026.2 complementary analysis from a transcriptome study in human hippocampal samples of different ages revealed a set of genes differentially expressed in aged individuals linked to inflammation and immune system pathways, DNA repair (RAD23) or neural activity.
Ander Saenz‐Antoñanzas +9 more
wiley +1 more source
Association of late childbearing with healthy longevity among the oldest-old in China [PDF]
Statistical analysis of a large and unique longitudinal data set demonstrates that late childbearing after age 35 or 40 is significantly associated with survival and healthy survival among very old Chinese women and men.
James W. Vaupel, Yi Zeng
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Journal of Microbiology and Biotechnology, 2019 Several studies have attempted to identify factors associated with longevity and maintenance of health in centenarians. In this study, we analyzed and compared the gut microbiota of centenarians in longevity villages with the elderly and adults in the ...
Bong-Soo Kim +8 more
semanticscholar +1 more source
Frontiers in Endocrinology, 2018 As the first time worldwide, this study aimed to investigate the relationships of hyperhomocysteinemia and hyperuricemia with metabolic syndrome (MetS) and renal function in Chinese centenarians. The China Hainan Centenarian Cohort Study was performed in
Shihui Fu +5 more
doaj +1 more source
Oldest Old Mortality in China [PDF]
We find that the Kannisto model, a two-parameter logistic formula, fits Han Chinese death rates at oldest-old ages better than the Gompertz and four other models. Chinese death rates appear to be roughly similar to Swedish and Japanese rates after age 97
James W. Vaupel, Yi Zeng
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Differential trends in the compression of mortality: Assessing the antecedents to current gaps in health expectancy in New Zealand [PDF]
, 2009 Health Expectancies (HEs) for New Zealand show significant differentials between Maori and non-Maori, but also by gender and period. These differentials correlate with findings from both generation and synthetic life-tables relating to New Zealand’s ...
Amey, Ben +4 more
core +1 more source
Depression Moderates the Frailty–Subjective Health Link among Chinese Near Centenarians and Centenarians [PDF]
, 2016 published_or_final_versio
Cheung, KSL +3 more
core +1 more source
Beyond the Kannisto-Thatcher Database on Old Age Mortality: an assessment of data quality at advanced ages [PDF]
The old age population in developed countries has been increasing remarkably, yet internationally comparable high quality data on oldest-old mortality remain relatively scarce.
Dmitri A. Jdanov +4 more
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