Results 91 to 100 of about 11,258 (207)

Neuropathology of the centenarian brains

Alzheimer Disease & Associated Disorders, 1985
100歳から115歳にわたる5例の長寿者の脳を病理学的に検討した.1) 症例はいずれも女性で, 従来ほとんど病気らしい病気をせず, 比較的長寿の家系のものが多い.2) 精神機能の障害は死亡の数年以内に目立ってきている.3) 死因は, 肺炎, 心不全, 肺癌, その他である.4) 全身臓器の著明な萎縮があり, 脳重は950～1,170gで, 全葉に回転萎縮がみられた.5) 脳に肉眼的粗大病変のあるものは3例で, 出血, 梗塞とも小さなものであった.6) 組織学的には, 生理的老年変化と関連した神経細胞数の減少, 萎縮, リポフスチン沈着, 軸索ジストロフィー, マリネスコ小体, トルペドーなどはいずれも高度であった.
M, Tomonaga, M, Yoshimura
openaire   +3 more sources

Electrocardiogram in centenarians

, 2005
Background: Electrocardiographic abnormalities in the very elderly have not yet been fully assessed.Aim: To evaluate ECG recordings obtained from centenarians.Methods: ECG tracings recorded at place of residence of 35 subjects aged 100-112 years (mean ...
Życzkowska, Jolanta, Grodzicki, Tomasz, Klich-Rączka, Alicja   +2 more
core   +1 more source

A case-only approach for assessing gene-sex interaction in human longevity [PDF]

As one aspect of the complex feature of longevity, gene-sex interaction plays an important role in influencing human life span. With advances in molecular genetics, more studies aimed at assessing gene-sex interaction are expected.
Karen Andersen-Ranberg, Bernard Jeune, Anatoli I. Yashin, Moniek De Maat, James W. Vaupel, Qihua Tan, Else M. Bladbjerg, Kaare Christensen   +7 more
core  

Centenarians in good health conditions

, 2002
The increased survival of the population represents the most relevant demographic phenomenon during the end of the 20th century. Aging of the population is correlated with two factors: (i) reduction of the birth rate, and (ii) decrease of mortality rate.
Berardelli M., Mari D., Grassi E., Sorbi S., Pini G., Bosi E., Capurso A., Solfrizzi V., Maugeri D., Bertolini S., Rapisarda R., Nicita Mauro V., Cossarizza A., Gaddi A., De Benedictis G., Battegazzore C., Casotti G., Senin U., Agretti M., Guerrini M., Falcone E., Deiana L., Frantone A., Perticone F., Nardi L., D'Addato S., Ferrari E., Varricchio M., Troiano L., Terrazzi P., Forconi S., Baggio G., Costelli P., Gambardella A., Carru C., De Luca M., Colacicco A. M., Trabucchi M., Bennati E., Marigliano V., Ferito L., Cappa G., Latorraca S., Sangiorgi Z., Prolisso G., Basile G., Rozzini R., Molla G., Boschi S., Manzoni M., Malaguarnera M., Frada' G., Sansoni P., Polidori M. C., Lavagetto G., Barbi C., Zoccolo A., Pollina R., Cherubini A., Barbagallo M., Bauco C., Monti D., Borriello C., Neri M., Boffelli S., Tomasello F. B., Pes G. M., Petruzzi E., Motta M., Bonafe' M., Salvioli G., Ferrario E., Passeri M., Duca F., Fabris F., Baldeli M. V.   +75 more
core   +2 more sources

Functional capacity and level of physical activity in centenarians of Florianópolis, Brazil

Revista da Educação Física, 2016
Aim: To compare the level of physical activity and functional capacity of centenarians from Florianópolis, Brazil. Methods: To measure the level of physical activity and functional capacity, pedometer and the Katz scale, respectively, were used.
Inês Amanda Streit, Artur Rodrigues Fortunato, Eduardo Hauser, Giovana Zarpellon Mazo   +3 more
doaj  

Lipid profile in elderly and centenarian subjects in Kazakhstan: a case-control study

Central Asian Journal of Medical Hypotheses and Ethics
Introduction. The health of centenarians is a major focus in global studies. Dyslipidemia is directly linked to the risk of cardiovascular diseases, which pose a growing burden on healthcare due to the increasing elderly population.
Yu. Ganzhula, Zh. Borykbay, V. Tkachev, S. Urazova, L. Chulenbayeva   +4 more
doaj   +1 more source

Centenarians' "holy" memory: is being positive enough?

, 2013
The authors compared 18 centenarians' (M age = 100.1years, SD = 1.8years) recognition memory for emotional (positive, negative, and religious) pictures with 18 older adults (M age = 75.2years, SD = 6.8years). Participants observed a series of images that
FAIRFIELD, Beth, DI DOMENICO, ALBERTO, MAMMARELLA, Nicola   +2 more
core   +1 more source

Mesaconic acid as a key metabolite with anti-inflammatory and anti-aging properties produced by Lactobacillus plantarum 124 from centenarian gut microbiota

npj Biofilms and Microbiomes
The gut microbiota of centenarians plays a vital role in promoting healthy longevity. We performed a cross-sectional study of 224 people from Jiaoling, China, which is globally recognised for the longevity of its residents.
Lei Wu, Hongxin He, Tingting Liang, Guowei Du, Longyan Li, Haojie Zhong, Ying Li, Jinke Zhang, Ning Chen, Tong Jiang, Juan Yang, Jiangyan Wang, Shuo Feng, Shenghua Lu, Hui Zhao, Qihui Gu, He Gao, Guanghui Li, Wenrui Xie, Lihao Wu, Qingping Wu, Xinqiang Xie, Xingxiang He   +22 more
doaj   +1 more source

Markers of Mitochondrial Function and DNA Repair Associated with Physical Function in Centenarians [PDF]

Mitochondrial dysfunction and genomic instability are key hallmarks of aging. The aim of this study was to evaluate whether maintenance of physical capacities at very old age is associated with key hallmarks of aging.
Hoei Rasmussen, Signe, Tinna Stevnsner, Signe Hoei Rasmussen, Bohr, Vilhelm A, Bohr, Vilhelm A., Myrup Holst, Camilla, Rasmussen, Signe Høi, Sánchez-Román Rojas, Inés, Christensen, Kaare; id_orcid, Mikael Thinggaard, Sanchez-Roman, Ines, Jonas Mengel-From, Beatriz Ferrando, Holst, Camilla Myrup, Thinggaard, Mikael, Ferrando, Beatriz, Kaare Christensen, Camilla Myrup Holst, Christensen, Kaare, Stevnsner, Tinna V., Mengel-From, Jonas, Stevnsner, Tinna, Vilhelm A. Bohr, Ines Sanchez-Roman, Thinggaard, Mikael; id_orcid   +24 more
core   +1 more source

Comprehensive quantitative score and metabonomics analysis of the effect of centenarians’ diet patterns on aging mice

Food Science and Human Wellness
Adhering to the concept of "asking for health and longevity from centenarians", this research first simulated the dietary structure characteristics of centenarians to construct the centenarians' diet pattern.
Qinren Zhang, Haijing Lan, Kai Ma, Feng Ji, Quanyang Li   +4 more
doaj   +1 more source