Results 81 to 90 of about 11,258 (207)

Low expression of CD39 and CD73 genes in centenarians compared with octogenarians [PDF]

, 2017
Ageing involves a progressive decline of the body’s regulatory systems including immune system. Adenosine regulates immune function by interaction with its receptors, mainly adenosine A2A receptor, present on the surface of immune cells.
Alfonso Cruz-Jentoft, Almudena Crooke, Martínez López, Joaquín, Martínez-Henández, Juan, Jesús Pintor, Crooke Álvarez, Almudena, Huete Toral, Fernando, Pintor, Jesús, Juan Martínez-Henández, Fernando Huete-Toral, Pintor Just, Jesús Jerónimo, Martínez-López, Joaquín, Crooke, Almudena, Cruz-Jentoft, Alfonso, Cruz Jentoft, Alfonso, Huete-Toral, Fernando, Joaquín Martínez-López, Martínez Henández, Juan   +17 more
core   +1 more source

A Cross-Sectional Study of Compositional and Functional Profiles of Gut Microbiota in Sardinian Centenarians

mSystems, 2019
Sardinia, Italy, has a high prevalence of residents who live more than 100 years. The reasons for longevity in this isolated region are currently unknown. Gut microbiota may hold a clue.
Lu Wu, Tiansheng Zeng, Angelo Zinellu, Salvatore Rubino, David J. Kelvin, Ciriaco Carru   +5 more
doaj   +1 more source

Modular Control of PEG‐Poly(2‐Oxazoline) Co‐Assembly Enables Tunable Aggregate Properties for Intraocular Pressure Management

Advanced Healthcare Materials, Volume 15, Issue 30, 14 August 2026.
A thermo‐responsive poly(2‐oxazoline)‐based injectable formulation is developed to modulate intraocular pressure (IOP) in both normal and hypotonic eyes. By adjusting the PEG content, the aggregation behavior is finely tuned, enabling IOP elevation without long‐term deposition.
Yuji Tanaka, Shohei Morikawa, Shigehito Osawa   +2 more
wiley   +1 more source

The mitochondrial DNA control region shows genetically correlated levels of heteroplasmy in leukocytes of centenarians and their offspring

BMC Genomics, 2007
Background Studies on heteroplasmy occurring in the mitochondrial DNA (mtDNA) control region (CR) in leukocytes of centenarians and younger subjects have shown that the C150T somatic transition is over-represented in centenarians.
Maletta Raffaele, Feraco Emidio, Mari Vincenzo, Bellizzi Dina, Dato Serena, Romeo Giuseppe, Scornaienchi Vittorio, Passarino Giuseppe, Rose Giuseppina, Bruni Amalia, Franceschi Claudio, De Benedictis Giovanna   +11 more
doaj   +1 more source

Survival differences among the oldest old in Sardinia: who, what, where, and why? [PDF]

A study of centenarians in Sardinia detected the existence of an area where the number of centenarians is higher than elsewhere, in particularly for men.
Rosa Maria Lipsi, Graziella Caselli
core  

Prevalence of functional dependence in Chinese centenarians and its relationship with serum vitamin D status

, 2018
Yao Yao,1,* Shihui Fu,2,* Qiuling Shi,3 Hao Zhang,4 Qiao Zhu,5 Fu Zhang,5 Fuxin Luan,5 Yali Zhao,5 Yao He1 1Institute of Geriatrics, Beijing Key Laboratory of Aging and Geriatrics, National Clinical Research Center for Geriatric Diseases, Chinese PLA ...
Zhang F, Luan F, Yao Y, Fu S, He Y, Shi Q, Zhang H, Zhu Q, Zhao Y   +8 more
core  

Relationships of Hyperhomocysteinemia and Hyperuricemia With Metabolic Syndrome and Renal Function in Chinese Centenarians

Frontiers in Endocrinology, 2018
As the first time worldwide, this study aimed to investigate the relationships of hyperhomocysteinemia and hyperuricemia with metabolic syndrome (MetS) and renal function in Chinese centenarians. The China Hainan Centenarian Cohort Study was performed in
Shihui Fu, Shihui Fu, Yao Yao, Yao Yao, Yali Zhao, Fuxin Luan   +5 more
doaj   +1 more source

Centenarians’ experience of the COVID pandemic in Switzerland

, 2022
Being considered as individuals with elevated risk of severe health reactions to the COVID19 infections, governments around the world have put in place wide-ranging measures to protect very old individuals from the virus.
Cavalli, Stefano, Gomes da Rocha, Carla, Jopp, Daniela, Uittenhove, Kim, Herrmann, François, Von Gunten, Armin, Ziade, Garnelle   +6 more
core   +1 more source

Estimating centenarians in Mexico: Trends, geographic distribution, and data quality challenges [PDF]

Demographic Research
BACKGROUND: The number of centenarians worldwide has increased considerably since 1950. However, most demographic research on population longevity has focused on high-income countries.
Elder Lara-Castaneda, Victor Garcia-Guerrero   +1 more
doaj   +1 more source

Thyroid nodules in centenarians: prevalence and relationship to lifestyle characteristics and dietary habits

, 2018
Yao Yao,1,* Xianghui Chen,2,* Shengzheng Wu,2 Liang Guo,3 Hao Zhang,4 Qiao Zhu,5 Jie Tang,3 Fuxin Luan,5 Yali Zhao,5 Faqin Lv,2 Yao He1 1Institute of Geriatrics, Beijing Key Laboratory of Aging and Geriatrics, National Clinical Research Center for ...
Tang J, Guo L, Yao Y, Lv FQ, He Y, Zhao YL, Wu SZ, Luan FX, Zhang H, Chen XH, Zhu Q   +10 more
core