Results 11 to 20 of about 25,204 (254)

Global Research on Centenarians: A Historical and Comprehensive Bibliometric Analysis from 1887 to 2023 [PDF]

Annals of Geriatric Medicine and Research
Background Centenarians are considered the most successful human biological aging model. However, the characteristics and patterns of research among centenarians have not been described or analyzed.
Ivan David Lozada-Martinez, Maria Carolina Diazgranados-Garcia, Sandra Castelblanco-Toro, Juan-Manuel Anaya   +3 more
doaj   +2 more sources

Centenarians Alleviate Inflammaging by Changing the Ratio and Secretory Phenotypes of T Helper 17 and Regulatory T Cells

Frontiers in Pharmacology, 2022
The immune system of centenarians remains active and young to prevent cancer and infections. Aging is associated with inflammaging, a persistent low-grade inflammatory state in which CD4+ T cells play a role. However, there are few studies that have been
Lixing Zhou, Meiling Ge, Yan Zhang, Xiaochu Wu, Mi Leng, Chunmei Gan, Yi Mou, Jiao Zhou, Jiao Zhou, C Alexander Valencia, C Alexander Valencia, C Alexander Valencia, Qiukui Hao, Bin Zhu, Biao Dong, Biao Dong, Birong Dong   +16 more
doaj   +2 more sources

Descriptive and predictive analysis identify centenarians' characteristics from the Basque population

Frontiers in Public Health, 2023
BackgroundCentenarians exhibit extreme longevity and have been postulated, by some researchers, as a model for healthy aging. The identification of the characteristics of centenarians might be useful to understand the process of human aging.MethodsIn ...
Sara Cruces-Salguero, Igor Larrañaga, Igor Larrañaga, Javier Mar, Javier Mar, Javier Mar, Ander Matheu, Ander Matheu, Ander Matheu   +8 more
doaj   +2 more sources

Centenarians, semi and supercentenarians, COVID-19 and Spanish flu: a serological assessment to gain insight into the resilience of older centenarians to COVID-19

Immunity & Ageing
Background Although it is well known that the older people have been the most susceptible to COVID-19, there are conflicting data on the susceptibility of centenarians.
Claudia Maria Trombetta, Giulia Accardi, Anna Aiello, Anna Calabrò, Calogero Caruso, Mattia Emanuela Ligotti, Serena Marchi, Emanuele Montomoli, Martin Mayora Neto, Nigel Temperton, Giuseppina Candore   +10 more
doaj   +2 more sources

A Cross-Sectional Study of Compositional and Functional Profiles of Gut Microbiota in Sardinian Centenarians

mSystems, 2019
Sardinia, Italy, has a high prevalence of residents who live more than 100 years. The reasons for longevity in this isolated region are currently unknown. Gut microbiota may hold a clue.
Lu Wu, Tiansheng Zeng, Angelo Zinellu, Salvatore Rubino, David J. Kelvin, Ciriaco Carru   +5 more
doaj   +2 more sources

Blood biomarker profiles and exceptional longevity: comparison of centenarians and non-centenarians in a 35-year follow-up of the Swedish AMORIS cohort

GeroScience, 2023
Comparing biomarker profiles measured at similar ages, but earlier in life, among exceptionally long-lived individuals and their shorter-lived peers can improve our understanding of aging processes.
Shunsuke Murata, M. Ebeling, A. Meyer, K. Schmidt‑Mende, N. Hammar, K. Modig   +5 more
semanticscholar   +1 more source

A Comprehensive Analysis of Cytokine Network in Centenarians

International Journal of Molecular Sciences, 2023
Cytokines have been investigated extensively in elderly people, with conflicting results. We performed a comprehensive analysis of the plasma levels of 62 cytokines and growth factors involved in the regulation of the immune system, in healthy ...
M. Pinti, L. Gibellini, D. Lo Tartaro, S. De Biasi, M. Nasi, R. Borella, L. Fidanza, Anita Neroni, L. Troiano, C. Franceschi, A. Cossarizza   +10 more
semanticscholar   +1 more source

Cognitive Health of Nonagenarians in Southern Italy: A Descriptive Analysis from a Cross-Sectional, Home-Based Pilot Study of Exceptional Longevity (Cilento Initiative on Aging Outcomes Or CIAO). [PDF]

, 2020
Background: Nonagenarians and centenarians (NCs) are an extremely fragile population, particularly in regard to their physical and cognitive function.
Antonini, Paola, Brenner, David A, D'Arena, Giovanni, Jeste, Dilip V, Lucibello, Serena Grazia, Marino, Rosella, Pizza, Vincenzo, Rizzo, Marianna, Somma, Salvatore Di   +8 more
core   +1 more source

Outcomes of hip fracture in centenarians: a systematic review and meta-analysis

European Geriatric Medicine, 2023
We aimed to determine outcomes of hip fracture in centenarians. One-year mortality following a hip fracture was 53.8% (95% CI 47.2 to 60.3%). Dementia (26.2%, 95% CI 15.7 to 38.2%) and hypertension (15.6%, 95% CI 3.4 to 33.1%) were the most common ...
D. A. Abelleyra Lastoria, C. K. Benny, Toby O. Smith, C. Hing   +3 more
semanticscholar   +1 more source

Role of Sex and Age in Fatal Outcomes of COVID-19: Women and Older Centenarians Are More Resilient

International Journal of Molecular Sciences, 2023
In the present paper, we have analysed the role of age and sex in the fatal outcome of COVID-19, as there are conflicting results in the literature. As such, we have answered three controversial questions regarding this aspect of the COVID-19 pandemic ...
C. Caruso, Gabriella Marcon, G. Accardi, A. Aiello, Anna Calabrò, M. E. Ligotti, M. Tettamanti, Claudio Franceschi, G. Candore   +8 more
semanticscholar   +1 more source