Results 1 to 10 of about 403,008 (155)

Feline Calicivirus Infection Manipulates Central Carbon Metabolism [PDF]

Veterinary Sciences
Viruses can manipulate the host metabolism to achieve optimal replication conditions, and central carbon metabolism (CCM) pathways are often crucial in determining viral infections.
Guangrong Zhao, Hongwei Zhu, Xiu Xue, Chenpei Zhao, Xin Yu, Linlin Jiang, Jingxian Cong, Yang Liu, Yuanlong He, Jianlong Zhang, Xingxiao Zhang   +10 more
doaj   +2 more sources

Modular deregulation of central carbon metabolism for efficient xylose utilization in Saccharomyces cerevisiae [PDF]

Nature Communications
The tightly regulated central carbon metabolism in Saccharomyces cerevisiae, intricately linked to carbon sources utilized, poses a significant challenge to engineering efforts aimed at increasing the flux through its different pathways. Here, we present
Xiaowei Li, Yanyan Wang, Xin Chen, Leon Eisentraut, Chunjun Zhan, Jens Nielsen, Yun Chen   +6 more
doaj   +2 more sources

A Mathematical Model of Metabolism and Regulation Provides a Systems-Level View of How Escherichia coli Responds to Oxygen [PDF]

Frontiers in Microbiology, 2014
The efficient redesign of bacteria for biotechnological purposes, such as biofuel production, waste disposal or specific biocatalytic functions, requires a quantitative systems-level understanding of energy supply, carbon and redox metabolism.
Michael eEderer, Sonja eSteinsiek, Stefan eStagge, Matthew eRolfe, Alexander eTer Beek, David eKnies, Joost eTeixeira de Mattos, Thomas eSauter, Jeffrey eGreen, Robert ePoole, Katja eBettenbrock, Oliver eSawodny   +11 more
doaj   +19 more sources

Top-Down, Knowledge-Based Genetic Reduction of Yeast Central Carbon Metabolism [PDF]

mBio, 2022
Saccharomyces cerevisiae, whose evolutionary past includes a whole-genome duplication event, is characterized by a mosaic genome configuration with substantial apparent genetic redundancy.
Eline D. Postma, Lucas G. F. Couwenberg, Roderick N. van Roosmalen, Jordi Geelhoed, Philip A. de Groot, Pascale Daran-Lapujade   +5 more
doaj   +2 more sources

Control of renal central carbon metabolism by heme oxygenase-1 [PDF]

iScience
Summary: Metabolic adaptation is an integral part of the organismal stress-response. In this study, we investigate the role of Hmox1 in mediating metabolic adaptation under both physiological and hemolytic stress conditions.
Joel Guerra, Elisa Jentho, Sascha Schäuble, Brendon P. Scicluna, Wolfgang Vivas, Dania Martínez-Alarcón, Marco Groth, Emma King, Franziska Röstel, Gianna Hirth, Miguel P. Soares, Thorsten Wiech, Gianni Panagiotou, Michael Bauer, Verena Hoerr, Sebastian Weis   +15 more
doaj   +2 more sources

Repressed Central Carbon Metabolism and Its Effect on Related Metabolic Pathways in Cefoperazone/Sulbactam-Resistant Pseudomonas aeruginosa

Frontiers in Microbiology, 2022
Metabolic shift and antibiotic resistance have been reported in Pseudomonas aeruginosa. However, the global metabolic characteristics remain largely unknown.
Yue-tao Chen, Ke-xin Yang, Zhen-yuan Dai, Huan Yi, Xuan-xian Peng, Xuan-xian Peng, Hui Li, Hui Li, Zhuang-gui Chen   +8 more
doaj   +1 more source

Investigation into the flux distribution of central carbon metabolism in Corynebacterium glutamicum using principal component analysis [PDF]

Archives of Biological Sciences, 2015
Central carbon metabolism is the main source of energy required by organisms and it provides precursors for other in vivo metabolic processes.
Shang Chuanyu, Zhou Xiangfei, Zhou Wenwei, Xie Xiaoyao, Yi Yin   +4 more
doaj   +1 more source

A metabolic checkpoint protein GlmR is important for diverting carbon into peptidoglycan biosynthesis in Bacillus subtilis. [PDF]

PLoS Genetics, 2018
The Bacillus subtilis GlmR (formerly YvcK) protein is essential for growth on gluconeogenic carbon sources. Mutants lacking GlmR display a variety of phenotypes suggestive of impaired cell wall synthesis including antibiotic sensitivity, aberrant cell ...
Vaidehi Patel, Qun Wu, Pete Chandrangsu, John D Helmann   +3 more
doaj   +1 more source

Development of a portable leaf photosynthesis and volatile organic compounds emission system. [PDF]

, 2020
Understanding how plant carbon metabolism responds to environmental variables such as light is central to understanding ecosystem carbon cycling and the production of food, biofuels, and biomaterials. Here, we couple a portable leaf photosynthesis system
de Oliveira Piva, Luani Rosa, Gimenez, Bruno O, Jardine, Kolby J, Robles, Emily, Zorzanelli, Raquel F   +4 more
core   +3 more sources

Gene Dispensability in Escherichia coli Grown in Thirty Different Carbon Environments

mBio, 2020
Central metabolism is a topic that has been studied for decades, and yet, this process is still not fully understood in Escherichia coli, perhaps the most amenable and well-studied model organism in biology.
Madeline Tong, Shawn French, Sara S. El Zahed, Wai kit Ong, Peter D. Karp, Eric D. Brown   +5 more
doaj   +1 more source