Results 201 to 210 of about 403,157 (288)

A GTP-driven central carbon metabolism in the cellulolytic bacterium Ruminiclostridium cellulolyticum. [PDF]

Commun Biol
Liu N, Vita N, Holmière M, Gagnot S, Brasseur G, de Philip P, Pagès S, Perret S, Fierobe HP.   +8 more
europepmc   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

The Cyclin-Dependent Kinase activity modulates the central carbon metabolism in maize during germination. [PDF]

Physiol Plant
Lara-Núñez A, Garza-Aguilar SM, Páez-Franco JC, de Dios Galindo-de-la-Rosa J, Vallejo-Becerra V.   +4 more
europepmc   +1 more source

Lactucin, a Bitter Sesquiterpene from Cichorium intybus, Inhibits Cancer Cell Proliferation by Downregulating the MAPK and Central Carbon Metabolism Pathway. [PDF]

Molecules, 2022
Imam KMSU, Tian Y, Xin F, Xie Y, Wen B.
europepmc   +1 more source

Dual‐Functional Polyphosphoesters for Gene Delivery: Synergistic Effects of Guanidinium and Hydrophobic Side Chains in Degradable Polymers

Advanced Healthcare Materials, EarlyView.
This study presents guanidinium‐ and indole‐functionalized polyphosphoesters as degradable, non‐viral gene delivery vectors. Through precise tuning of charge density and hydrophobicity, these polymers form stable polyplexes with low toxicity. Remarkably, minor structural changes yield up to 200‐fold differences in transfection efficiency, highlighting ...
Markus Kötzsche, Andreas Dzierza, Jan Egger, Timo Rheinberger, Christin Weilandt, Frederik R. Wurm, Ivo Nischang, Dagmar Fischer, Kalina Peneva   +8 more
wiley   +1 more source

Reactive oxygen species-post translational modifications-central carbon metabolism regulatory loop: coordination of redox homeostasis and carbon flux allocation in plants under abiotic stress. [PDF]

Front Plant Sci
Bao L, Wang W, Li M, Liu J, Liu J, Alifu G, Wang D, Liang X, Mao T, Zhai Y.   +9 more
europepmc   +1 more source

Ribitol alters multiple metabolic pathways of central carbon metabolism with enhanced glycolysis: A metabolomics and transcriptomics profiling of breast cancer. [PDF]

PLoS One, 2022
Tucker JD, Doddapaneni R, Lu PJ, Lu QL.
europepmc   +1 more source

A Biomimetic Buffering Hydrogel Scaffold for Long‐Term Culture of Patient‐Derived Tumor Organoids

Advanced Healthcare Materials, EarlyView.
A biomimetic fibrous buffering hydrogel controls the local acidification at the tumoroid/hydrogel interface at the physiologically relevant level over 21‐day culture. The buffering effect promotes cancer cell proliferation in the tumoroids and supports the structural integrity and mechanical properties of the hydrogel scaffold over long‐term tumoroid ...
Elizaveta Gusarova, Fatemeh Ahmadi, Jennifer Cruickshank, Zheyuan Miao, Mariia Moshkova, Iuliia Pilipenko, David W. Cescon, Eugenia Kumacheva   +7 more
wiley   +1 more source

Expanding the FurC (PerR) regulon in Anabaena (Nostoc) sp. PCC 7120: Genome-wide identification of novel direct targets uncovers FurC participation in central carbon metabolism regulation. [PDF]

PLoS One, 2023
Sarasa-Buisan C, Guío J, Peleato ML, Fillat MF, Sevilla E.   +4 more
europepmc   +1 more source

Biofabrication of Endothelialized, Intrinsically Vascularized 3D‐Printed Recombinant Spider Silk Scaffolds

Advanced Healthcare Materials, EarlyView.
This study evaluates 3D‐printed recombinant spider silk hydrogel eADF4(C16)‐RGD in a rat AV loop model for tissue engineering. Constructs with T17b endothelial progenitor cells showed enhanced vascularization and biodegradation. Results highlight the importance of scaffold design and cellular integration in improving vascular density and overall ...
Claire M. Weinhold, Stefanie Heltmann‐Meyer, Xuen J. Ng, Thomas Scheibel, Tobias Fey, Harald Wajant, Carol Geppert, Andreas Arkudas, Dominik Steiner, Raymund E. Horch   +9 more
wiley   +1 more source