Results 21 to 30 of about 403,157 (288)
Reprogramming of central carbon metabolism in hepatocellular carcinoma
Biomedicine & Pharmacotherapy, 2022 In multicellular organisms, nutrient uptake and its metabolism are subject to stringent regulation to maintain cellular integrity and prevent aberrant cell proliferation. However, the altered signaling pathways and gene expression disorders in hepatocellular carcinoma (HCC) induce the transformation of metabolic patterns.
Haoming, Xia +4 more
openaire +2 more sources
Roles of Candida albicans Mig1 and Mig2 in glucose repression, pathogenicity traits, and SNF1 essentiality. [PDF]
, 2020 Metabolic adaptation is linked to the ability of the opportunistic pathogen Candida albicans to colonize and cause infection in diverse host tissues. One way that C.
Filler, Scott G +7 more
core +3 more sources
Manganese Utilization in Salmonella Pathogenesis: Beyond the Canonical Antioxidant Response
Frontiers in Cell and Developmental Biology, 2022 The metal ion manganese (Mn2+) is equally coveted by hosts and bacterial pathogens. The host restricts Mn2+ in the gastrointestinal tract and Salmonella-containing vacuoles, as part of a process generally known as nutritional immunity.
Siva R. Uppalapati +2 more
doaj +1 more source
Interferon-stimulated gene products as regulators of central carbon metabolism. [PDF]
FEBS J, 2021 In response to viral infections, the innate immune system rapidly activates expression of several interferon‐stimulated genes (ISGs), whose protein and metabolic products are believed to directly interfere with the viral life cycle. Here, we argue that biochemical reactions performed by two specific protein products of ISGs modulate central carbon ...
Ebrahimi KH +3 more
europepmc +5 more sources
mSystems, 2021 Glucose-6-phosphate dehydrogenase (G6PDH) is widely distributed in nature and catalyzes the first committing step in the oxidative branch of the pentose phosphate (PP) pathway, feeding either the reductive PP or the Entner-Doudoroff pathway.
Daniel Christoph Volke +2 more
doaj +1 more source
A Shift in Central Metabolism Accompanies Virulence Activation in Pseudomonas aeruginosa. [PDF]
, 2020 The availability of energy has significant impact on cell physiology. However, the role of cellular metabolism in bacterial pathogenesis is not understood.
Chacko, Jenu V +4 more
core +1 more source
Microbial Cell Factories, 2020 Background Sugars and triglycerides are common carbon sources for microorganisms. Nonetheless, a systematic comparative interpretation of metabolic changes upon vegetable oil or glucose as sole carbon source is still lacking. Selected fungi that can grow
Arief Izzairy Zamani +9 more
doaj +1 more source
Frontiers in Bioengineering and Biotechnology, 2022 Serum-free cultures are preferred for application in clinical cell therapy and facilitate the purification processes of bioproducts, such as vaccines and recombinant proteins.
Mi Jang, Ellen Sofie Pete, Per Bruheim
doaj +1 more source
Organellar carbon metabolism is co-ordinated with distinct developmental phases of secondary xylem [PDF]
, 2019 Subcellular compartmentation of plant biosynthetic pathways in the mitochondria and plastids requires coordinated regulation of nuclear encoded genes, and the role of these genes has been largely ignored by wood researchers. In this study, we constructed
Fierro Gutierrez, Ana Carolina Elisa +4 more
core +2 more sources
Evolution of Central Carbon Metabolism [PDF]
Molecular Cell, 2010 Organisms share a common core to their metabolic networks. But what determined this: chance, chemical necessity, or evolutionary optimization? In this issue of Molecular Cell, Noor et al. (2010) provide new evidence for selection of a network with optimal features from a broader set of possibilities.
openaire +2 more sources