Results 91 to 100 of about 215,784 (311)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
APPLICATION OF CENTRAL COMPOSITE DESIGN FOR OPTIMIZATION THE DETERMINATION OF LEAD USING ADSORPTIVE CATHODIC STRIPPING VOLTAMMETRY [PDF]
, 2016 This paper describes an optimization method for rapid determination of lead from Maninjau lake waters by adsorptive cathodic stripping voltammetry using central composite design.
Deswati, Deswati +4 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Central Composite Design and industrial data, PCBN tools 7025AWG
, 2017 Central Composite Design (CCD) with 3 controllable variables (x) and 19 responses (Y) related to the H13 hardened steel turning with Wiper PCBN 7025 Wiper tools. The 19 response surfaces were defined to focus on five important process dimensions: quality,
COSTA, D (via Mendeley Data) +2 more
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Thermoelastic stress analysis of laminated composite materials
, 2009 In this work thermoelastic stress analysis (TSA) is used to obtain quantitative stress/strain data from a variety of multi-directional laminated composites. In order to interpret the thermoelastic signal correctly the source of the thermoelastic response
Sambasivam, Shamala
core
The independent variables and coded values of variables used in central composite rotary design.
, 2014 The independent variables and coded values of variables used in central composite rotary design.
Yun-Jaie Choi (49981) +7 more
core +1 more source
Acta Universitatis Cibiniensis. Series E: Food Technology, 2016 The objective of the present study was to obtain the optimum proportion of the carbon source and prebiotics for Bifidobacterium bifidum BB01 by the central composite design (CCD).
Shu Guowei +4 more
doaj +1 more source
Dyna, 2019 Ultrasonic-assisted extraction (UAE) was applied to extract total carotenoids from dried peach palm peel using soy oil as extraction solvent. Optimization of UAE parameters of total carotenoid extraction from dried peel was done using Response Surface ...
Jader Martínez Girón +2 more
doaj +1 more source