Results 191 to 200 of about 215,784 (311)

Enhancing wool dyeing with clove bud (Syzygium aromaticum) based natural dye via microwave treatment using a central composite design. [PDF]

Sci Prog, 2023
Yameen M, Asghar F, Adeel S, Haider MZ, Özomay M, Aftab M, Mia R.   +6 more
europepmc   +1 more source

Design And Development of Emulgel Containing Ibuprofen Using Central Composite Design

Ibuprofen is chosen as the drug in the emulgel.  Emulgel accommodates oil soluble drugs and enhances penetration of the drug. Ibuprofen (iso-butyl-phenyl-propionic acid) is a nonsteroidal anti-inflammatory drug (NSAID) that is used for treating pain, fever, and inflammation. Peceol oil is chosen in emulgel .
openaire   +2 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Precision optimization of standardized ileal digestible lysine:methionine: Threonine ratios in low-protein male broiler diets using central composite design. [PDF]

Poult Sci
Chang C, Feng Y, Wang S, Zhang A, Wu Z, Yang Y.   +5 more
europepmc   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Valorization of marble sludge waste in biodiesel production using a central composite design. [PDF]

Sci Rep
El-Naggar KA, Mansor ES, Maafa IM, Abutaleb A, Yousef A, Matar SM, Hamid EMA.   +6 more
europepmc   +1 more source

Optimization of Cold Brew Coffee Using Central Composite Design and Its Properties Compared with Hot Brew Coffee. [PDF]

Foods, 2023
Zakaria NH, Whanmek K, Thangsiri S, Chathiran W, Srichamnong W, Suttisansanee U, Santivarangkna C.   +6 more
europepmc   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Water-Fertilizer Synergistic Effects and Resource Optimization for Alfalfa Production: A Central Composite Design and Response Surface Methodology Approach. [PDF]

Plants (Basel)
Mu G, Jiang Y, Li H, Wei S, Qi G, Kang Y, Yin M, Ma Y, Wang Y, Wang Y, Wang J.   +10 more
europepmc   +1 more source

Central composite design driven optimization of sustainable stability indicating HPLC method for the determination of Tigecycline and greenness assessment. [PDF]

F1000Res, 2023
Hafez HM, Barghash SS, Soliman MM, Soltan MK, Abd Elrahman M, Katamesh NS.   +5 more
europepmc   +1 more source