Molecular Oncology, EarlyView.Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Optimization of Phenolic and Flavonoid Extraction From Bee Bread Using Response Surface Methodology and Central Composite Design, and Evaluation of Antimicrobial Activity. [PDF]
Food Sci NutrKeyvan N +6 more
europepmc +1 more source
Application of Central Composite Design and Superimposition Approach for Optimization of Drying Parameters of Pretreated Cassava Flour. [PDF]
Foods, 2023 Nainggolan EA, Banout J, Urbanova K.
europepmc +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Modeling and optimization of Multi-Waste foam geopolymers using central composite design and neural networks. [PDF]
Sci RepNoui A +6 more
europepmc +1 more source
Molecular Oncology, EarlyView.Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
, 2008 This 7-page laboratory activity guide from Edmonds College introduces undergraduate students to how materials properties are used in engineering design across a modular activity spanning 3-5 class sessions. Students simulate the use of composite
Johnson, Craig
core
Development of Optimized Bioactive Nanocomposite Films Using a Central Composite Design for Control of Microbial Contamination in Stored Rice. [PDF]
J Food SciBegum T +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
RETRACTION: Optimization and Modeling of Cr (VI) Removal from Tannery Wastewater onto Activated Carbon Prepared from Coffee Husk and Sulfuric Acid (H<sub>2</sub>SO<sub>4</sub>) as Activating Agent by Using Central Composite Design (CCD). [PDF]
J Environ Public HealthEnvironmental And Public Health JO.
europepmc +1 more source