Results 151 to 160 of about 215,784 (311)

Numerical modeling and optimization of self-compacting mortars: central composite design approach with

, 2022
The current work developed Statistical models to reach high-performance self compacting cement-based mortars for structural purposes. A central composite design approach was employed to describe mortar fresh and hardened properties (mechanical ...
Nara Cangussu, Lino Maia, Maia, Lino, Cangussu, Nara, Ana Mafalda Matos, Matos, Ana Mafalda   +5 more
core  

Application of response surface methodology for the optimization of arabinose biotransformation to arabitol by Candida parapsilosis

Open Life Sciences, 2013
Kordowska-Wiater Monika, Kubik-Komar Agnieszka, Targoński Zdzisław   +2 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Optimization of the culture medium and fermentation conditions for Pseudomonas fluorescens-based biofertilizers production

Biotecnología Vegetal, 2019
In Cuba, a biofertilizer has been developed based on a Pseudomonas fluorescens strain phosphate solubilizer. Given the need to standardize its industrial scale up, this work aimed to optimize the culture medium and the fermentation conditions.
María Cristina Pérez Peñaranda, Julio Oramas García, Emilio Arcadio Sotolongo Valdés, Alina Miranda Galuzzo, Yoandra Román Tabio, Alain González Soto   +5 more
doaj  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

The 2³ full factorial and face-centred central composite design [58].

The 23 full factorial and face-centred central composite design [58].
Shazarel Shamsudin (18156067), Nayef Abdulwahab Mohammed Alduais (18156076), Sami Al-Alimi (17144826), Yahya M. Altharan (18156064), Mohd Amri Lajis (18156070), Nur Kamilah Yusuf (18156073), Atef M. Ghaleb (6565109), Wenbin Zhou (295899)   +7 more
core   +1 more source

Optimization Process Of Biodiesel Production With Ultrasound Assisted By Using Central Composite Design Methods [PDF]

, 2012
The objective of this research is to optimize of biodiesel production with ultrasound assisted. Optimization was used central composite design methods. Biodiesel was produced from frying oil with KOH catalyst and ultrasonic assisted. The variables were
Yuariski, Oki, Murwono, Djoko, Widayat, Widayat, Satriadi, Hantoro   +3 more
core  

OPTIMIZATION OF MICROWAVE-ASSISTED EXTRACTION (MAE) OF CINNAMON (CINNAMOMUM BURMANNII) OLEORESIN USING RESPONSE SURFACE METHODOLOGY

Scientific Study & Research: Chemistry & Chemical Engineering, Biotechnology, Food Industry, 2019
Cinnamon (Cinnamomum burmanii) oleoresin is produced from the extraction of the cinnamon plant, mainly its bark. Microwave-Assisted Extraction (MAE) can produce this oleoresin with many advantages i.e.
DARMANTO
doaj  

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source