Results 141 to 150 of about 198,147 (243)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt, Ana‐Maria Sandru, Georg Vucak, Sebastian Didusch, Biljana Riemelmoser, Karin Ehrenreiter, Markus Hartl, Lukas A. Huber, Manuela Baccarini   +8 more
wiley   +1 more source

Optimization of Cassava Starch/Onion Peel Powder-Based Bioplastics: Influence of Composition on Mechanical Properties and Biodegradability Using Central Composite Design. [PDF]

Foods
Torche A, Toufik C, Djeghim F, Sanah I, Arhab R, D'Elia M, Rastrelli L.   +6 more
europepmc   +1 more source

Enhancing wool dyeing with clove bud (Syzygium aromaticum) based natural dye via microwave treatment using a central composite design. [PDF]

Sci Prog, 2023
Yameen M, Asghar F, Adeel S, Haider MZ, Özomay M, Aftab M, Mia R.   +6 more
europepmc   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Precision optimization of standardized ileal digestible lysine:methionine: Threonine ratios in low-protein male broiler diets using central composite design. [PDF]

Poult Sci
Chang C, Feng Y, Wang S, Zhang A, Wu Z, Yang Y.   +5 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Valorization of marble sludge waste in biodiesel production using a central composite design. [PDF]

Sci Rep
El-Naggar KA, Mansor ES, Maafa IM, Abutaleb A, Yousef A, Matar SM, Hamid EMA.   +6 more
europepmc   +1 more source

Optimization of Cold Brew Coffee Using Central Composite Design and Its Properties Compared with Hot Brew Coffee. [PDF]

Foods, 2023
Zakaria NH, Whanmek K, Thangsiri S, Chathiran W, Srichamnong W, Suttisansanee U, Santivarangkna C.   +6 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Water-Fertilizer Synergistic Effects and Resource Optimization for Alfalfa Production: A Central Composite Design and Response Surface Methodology Approach. [PDF]

Plants (Basel)
Mu G, Jiang Y, Li H, Wei S, Qi G, Kang Y, Yin M, Ma Y, Wang Y, Wang Y, Wang J.   +10 more
europepmc   +1 more source