Results 121 to 130 of about 215,784 (311)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Central composite rotatable design and four response variables for optimization of the extraction process.

, 2016
Central composite rotatable design and four response variables for optimization of the extraction process.
Yanping Luo (724724), Wei Zhang (405), Wencheng Hou (3111540), Guode Chen (3111537)   +3 more
core   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Optimization of the culture medium and fermentation conditions for Azotobacter chroococcum based biofertilizers production

Biotecnología Vegetal, 2020
In Cuba, a biofertilizer has been developed based on a nitrogen fixer Azotobacter chroococcum strain. This work aimed to optimize the culture medium and the fermentation conditions for industrial scale.
María Cristina Pérez Peñaranda, Julio Oramas García , Emilio Arcadio Sotolongo Valdés , Yoandra Román Tabio, Héctor López Rodriguez   +4 more
doaj  

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Fully reversible reinforcement of softwood beams with unbonded composite plates

, 2016
In this paper, results of flexure tests aimed at improving the structural behaviour of softwood beams reinforced with unglued composite plates and at developing an effective alternative to the use of organic resins are presented.
Borri, Antonio, Castori, Giulio, Speranzini, Emanuela, Corradi, Marco   +3 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Experimental range and level of central composite design for independent input variables in coded terms.

, 2015
Experimental range and level of central composite design for independent input variables in coded terms.
Michael Richter (13980), Pascal Ruedin (750180), André Hach (750182), Herbert Christen (750183), Mark Schubert (530084), Chiara Civardi (750181)   +5 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Process variables used central composite design with actual factor levels corresponding to coded factor levels.

, 2014
Process variables used central composite design with actual factor levels corresponding to coded factor levels.
Yu fei Zhang (563158), Guang hui Ma (563160), Song ping Zhang (563157), Jian dong Cui (5659012), Li li Cui (563156), Zhi guo Su (563159)   +5 more
core   +1 more source