Results 131 to 140 of about 198,147 (243)

Development of Optimized Bioactive Nanocomposite Films Using a Central Composite Design for Control of Microbial Contamination in Stored Rice. [PDF]

J Food Sci
Begum T, Follett PA, Sharaby MR, Shankar S, Salmieri S, Lacroix M.   +5 more
europepmc   +1 more source

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Central composite design optimized fluorescent method using dual doped graphene quantum dots for lacosamide determination in biological samples. [PDF]

Sci Rep
Serag A, Alzhrani RM, Alnemari RM, Abduljabbar MH, Almalki AH.   +4 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Development of a green spectrofluorimetric method for mefenamic acid determination using Rhodamine 6G with mechanistic investigation and central composite design optimization. [PDF]

RSC Adv
Alqahtani AS, Abduljabbar MH, Alnemari RM, Alaqel SI, Serag A, Almalki AH.   +5 more
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

RETRACTION: Optimization and Modeling of Cr (VI) Removal from Tannery Wastewater onto Activated Carbon Prepared from Coffee Husk and Sulfuric Acid (H₂SO₄) as Activating Agent by Using Central Composite Design (CCD). [PDF]

J Environ Public Health
Environmental And Public Health JO.
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

Hyperproduction of nattokinase from Bacillus subtilis VIT MS2 using random mutagenesis and statistical optimization through central composite design. [PDF]

BMC Microbiol
S MK, V M, M M, C SD.
europepmc   +1 more source

Continuous treatment of highly concentrated tannery wastewater using novel porous composite beads: Central composite design optimization study. [PDF]

J Environ Health Sci Eng, 2023
Lissaneddine A, Aziz K, Ouazzani N, El Achaby M, Haydari I, Mandi L, Aziz F.   +6 more
europepmc   +1 more source