Results 201 to 210 of about 753,418 (307)

Impact of atmospheric conditions on the flash-over voltage of the transmission line insulators using central composite design. [PDF]

Sci Rep
Ghaly RNR, Ibrahim A, Ghoneim SSM, Abu-Siada A, Bajaj M, Zaitsev I, Awad H.   +6 more
europepmc   +1 more source

Computational Approach to the Surface-Crosslinking Process of Superabsorbent Polymer via Central Composite Design. [PDF]

Polymers (Basel), 2022
Kim HC, Kwon YR, Kim JS, Kwon M, Kim JH, Kim DH.   +5 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Enhanced drilling waste-water treatment through magnetic nano-composite coagulant application: A central composite design study. [PDF]

Heliyon
Shadan B, Jafari A, Gharibshahi R.
europepmc   +1 more source

Formulation Development of Mirtazapine Liquisolid Compacts: Optimization Using Central Composite Design. [PDF]

Molecules, 2022
Naureen F, Shah Y, Shah SI, Abbas M, Rehman IU, Muhammad S, Hamdullah H, Goh KW, Khuda F, Khan A, Chan SY, Mushtaq M, Ming LC.   +12 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Predictive modeling and optimization of a waste cooking oil biodiesel/diesel powered CI engine: an RSM approach with central composite design. [PDF]

Sci Rep
Elkelawy M, El Shenawy EA, Bastawissi HA, Shams MM, P V E, Balasubramanian D, Anand V, Alwetaishi M.   +7 more
europepmc   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Optimization of cassava peel ash concrete using central composite design method. [PDF]

Sci Rep
Iro UI, Alaneme GU, Attah IC, Ganasen N, Duru SC, Olaiya BC.   +5 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source