Results 211 to 220 of about 751,175 (304)

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Use of Central Composite Design in Cellulosic Industrial Research: Dimethyl Formamide Pulping of Bagasse [PDF]

open access: yesعلوم و تکنولوژی پلیمر, 2006
P. Rezaee cherani   +5 more
doaj   +1 more source

Formulation Development of Mirtazapine Liquisolid Compacts: Optimization Using Central Composite Design. [PDF]

open access: yesMolecules, 2022
Naureen F   +12 more
europepmc   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Predictive modeling and optimization of a waste cooking oil biodiesel/diesel powered CI engine: an RSM approach with central composite design. [PDF]

open access: yesSci Rep
Elkelawy M   +7 more
europepmc   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Optimization of cassava peel ash concrete using central composite design method. [PDF]

open access: yesSci Rep
Iro UI   +5 more
europepmc   +1 more source

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