Results 31 to 40 of about 48,699 (150)

Less known aspects of central hypothyroidism: Part 1 – Acquired etiologies

Journal of Clinical & Translational Endocrinology, 2018
Central hypothyroidism (CH) is a rare cause of hypothyroidism. CH is frequently overlooked, as its clinical picture is subtle and includes non-specific symptoms; furthermore, if measurement of TSH alone is used to screen for thyroid function, TSH ...
Salvatore Benvenga, Marianne Klose, Roberto Vita, Ulla Feldt-Rasmussen   +3 more
doaj   +1 more source

Screening for Mutations in Isolated Central Hypothyroidism Reveals a Novel Mutation in Insulin Receptor Substrate 4

Frontiers in Endocrinology, 2021
BackgroundCentral hypothyroidism (CeH) is a rare condition affecting approximately 1:16 000- 100 000 individuals. Congenital forms can harm normal development if not detected and treated promptly.
Konrad Patyra, Konrad Patyra, Kristiina Makkonen, Kristiina Makkonen, Maria Haanpää, Maria Haanpää, Sinikka Karppinen, Liisa Viikari, Jorma Toppari, Jorma Toppari, Jorma Toppari, Mary Pat Reeve, Jukka Kero, Jukka Kero, Jukka Kero   +14 more
doaj   +1 more source

Less known aspects of central hypothyroidism: Part 2 – Congenital etiologies

Journal of Clinical & Translational Endocrinology, 2018
Central hypothyroidism (CH) occurs approximately in 1:50,000, and therefore is expected to be one thousand times rarer compared with primary hypothyroidism.
Salvatore Benvenga, Marianne Klose, Roberto Vita, Ulla Feldt-Rasmussen   +3 more
doaj   +1 more source

Pituitary function after transsphenoidal surgery including measurement of basal morning cortisol as predictor of adrenal insufficiency

Endocrine Connections, 2021
Introduction: Patients with pituitary adenomas undergoing transsphenoidal surgery require pre- and post-surgery examination of pituitary hormones. There is currently no consensus on how to evaluate the adrenal axis post-surgery.
Ida Staby, Jesper Krogh, Marianne Klose, Jonas Baekdal, Ulla Feldt-Rasmussen, Lars Poulsgaard, Jacob Bertram Springborg, Mikkel Andreassen   +7 more
doaj   +1 more source

Central TSH Dysregulation in a Patient with Familial Non-Autoimmune Autosomal Dominant Hyperthyroidism Due to a Novel Thyroid-Stimulating Hormone Receptor Disease-Causing Variant

Medicina, 2021
Background and Objectives. Familial non-autoimmune autosomal dominant hyperthyroidism (FNAH) is a rare cause of childhood hyperthyroidism. It is caused by the thyroid-stimulating hormone receptor (TSHR) gene variants. So far, only around 40 families with
Jasna Suput Omladic, Maja Pajek, Urh Groselj, Katarina Trebusak Podkrajsek, Magdalena Avbelj Stefanija, Mojca Zerjav Tansek, Primoz Kotnik, Tadej Battelino, Darja Smigoc Schweiger   +8 more
doaj   +1 more source

A Novel Pathogenic IGSF1 Variant in a Patient with GH and TSH Deficiency Diagnosed by High IGF-I Values at Transition to Adult Care

JCRPE, 2023
IGSF1 deficiency is a rare X-linked condition characterized by central hypothyroidism and a wide variety of other clinical features with variable prevalence, including a delayed pubertal testosterone rise and growth spurt in the context of normal or ...
Aslı Derya Kardelen, Esin Karakılıç Özturan, Şükran Poyrazoğlu, Firdevs Baş, Serdar Ceylaner, Sjoerd D. Joustra, Jan M. Wit, Feyza Darendeliler   +7 more
doaj   +1 more source

Congenital central hypothyroidism in a neonate born to thyrotoxic mother

Journal of Integrated Health Sciences, 2016
Maternal thyrotoxicosis is associated with significant risk of low birth weight premature & small for gestational age neonates; as well as intrauterine death.
M N Rasania, P M Modi
doaj   +1 more source

Partial Hypopituitarism Following Section Miscarriage: A Rare Presentation [PDF]

Journal of Clinical and Diagnostic Research, 2019
Hypopituitarism is a rare disorder with a prevalence of 45.5 cases per 100,000 individuals. The term “Selective or Partial Hypopituitarism” refers to the loss of at least one, but not all pituitary hormones.
Monisha Priyadarshini Kumar, Nairmeen Haller, Daniela Ciltea   +2 more
doaj   +1 more source

Unveiling the hidden: acquired pediatric hypothyroidism

Frontiers in Endocrinology
Acquired hypothyroidism is the most common thyroid disorder in children, with Hashimoto thyroiditis representing the leading cause in iodine-sufficient regions.
Mariacarolina Salerno, Mariacarolina Salerno, Donatella Capalbo, Donatella Capalbo, Mariella Valenzise, Raffaella Di Mase, Letteria Anna Morabito, Chiara Centonze, Malgorzata Gabriela Wasniewska   +8 more
doaj   +1 more source

Extreme Short Stature and Severe Neurological Impairment in a 17-Year-Old Male With Untreated Combined Pituitary Hormone Deficiency Due to POU1F1 Mutation

Frontiers in Endocrinology, 2019
Background: POU1F1 is an essential transcription factor for the differentiation, proliferation and survival of somatotrophs, lactotrophs, and thyrotrophs.
Hussein Majdoub, Serge Amselem, Marie Legendre, Shoshana Rath, Dani Bercovich, Yardena Tenenbaum-Rakover, Yardena Tenenbaum-Rakover   +6 more
doaj   +1 more source