Results 71 to 80 of about 2,021,144 (357)

CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2009-2013.

Neuro-Oncology, 2016
The objective of the CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2009–2013 is to provide a comprehensive summary of the current descriptive epidemiology of primary brain and other ...
Q. Ostrom, H. Gittleman, Jordan C Xu, Courtney Kromer, Yingli Wolinsky, C. Kruchko, J. Barnholtz-Sloan   +6 more
semanticscholar   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Biophysical characterization and ion transport with cell‐based and proteoliposome reconstitution assays of invertebrate K+‐Cl− cotransporters

FEBS Open Bio, EarlyView.
The K+‐Cl− cotransporters (KCCs) facilitate the symport of ions across the plasma membrane. They participate in physiological processes including neuronal regulation. Here, we characterized KCCs from Drosophila and Hydra vulgaris. Comparative analyses of transporters provide insights into the mechanism of KCC ion transport, regulation, and evolution ...
Satoshi Fudo, Marina Verkhovskaya, Coralie Di Scala, Claudio Rivera, Tommi Kajander   +4 more
wiley   +1 more source

Mitophagy-associated programmed neuronal death and neuroinflammation

Frontiers in Immunology
Mitochondria are crucial organelles that play a central role in cellular metabolism and programmed cell death in eukaryotic cells. Mitochondrial autophagy (mitophagy) is a selective process where damaged mitochondria are encapsulated and degraded through
Yanlin Zhu, Yanlin Zhu, Yanlin Zhu, Jianning Zhang, Jianning Zhang, Jianning Zhang, Quanjun Deng, Quanjun Deng, Quanjun Deng, Xin Chen, Xin Chen, Xin Chen   +11 more
doaj   +1 more source

Semi‐automated hippocampal avoidance whole‐brain radiotherapy planning

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Hippocampal avoidance whole‐brain radiotherapy (HA‐WBRT) is designed to spare cognitive function by reducing radiation dose to the hippocampus during the treatment of brain metastases. Current manual planning methods can be time‐consuming and may vary in quality, necessitating the development of automated approaches to streamline ...
Dong Joo Rhee, Subha Perni, Kelly J. Perrin, Kevin E. Casey, Alexandra O. Leone, Callistus M. Nguyen, Laurence E. Court, He Wang, Xin Wang, Eun Young Han   +9 more
wiley   +1 more source

Metastatic involvement of the central nervous system in gynecological cancer

Опухоли женской репродуктивной системы, 2014
Metastatic involvement of the central nervous system (CNS) is very rarely observed in gynecological cancer . Ten case histories were analyzed in patients with malignancies of the cervix uteri, endometrium, and ovaries concurrent with metastatic ...
Yu. S. Sidorenko, S. V. Grigorov, V. E. Plotnikova   +2 more
doaj   +1 more source

Glia as architects of central nervous system formation and function

Science, 2018
Glia constitute roughly half of the cells of the central nervous system (CNS) but were long-considered to be static bystanders to its formation and function.
N. J. Allen, D. Lyons
semanticscholar   +1 more source

Producing high quality cranial SRS plans with 4Pi planning technique in a commercial clinical solution

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose To generate high‐quality stereotactic radiosurgery (SRS) plans for single cranial lesions using 4Pi planning technique and compare these to our clinical “status quo” plans. Methods Eighteen vestibular schwannoma (VS) patients previously planned with Varian Eclipse RapidArc and treated on a Varian TrueBeam using 6FFF MV photon beams ...
Ganesh Narayanasamy, Nishan Shrestha, Milan Bimali, Fen Xia, Zhong Su   +4 more
wiley   +1 more source

Dosimetric evaluation and clinical application of collimated apertures with proton beam line scanning in stereotactic radiotherapy

Journal of Applied Clinical Medical Physics, EarlyView.
Abstract Purpose Stereotactic radiotherapy (SRT) is a highly effective treatment with precision for small, localized lesions. Proton therapy, characterized by the Bragg peak, offers superior dose conformity compared to photon‐based approaches. However, challenges remain in minimizing lateral penumbra and optimizing dose delivery, particularly for small
Chen‐Yu Chou, Hsiao‐Chieh Huang, Shen‐Hao Lee, Shih‐Ming Hsu   +3 more
wiley   +1 more source