Successes and challenges in modeling heterogeneous BRAFV600E mutated central nervous system neoplasms [PDF]
Central nervous system (CNS) neoplasms are difficult to treat due to their sensitive location. Over the past two decades, the availability of patient tumor materials facilitated large scale genomic and epigenomic profiling studies, which have resulted in
Yao Lulu Xing +2 more
doaj +2 more sources
The Continuing Value of Ultrastructural Observation in Central Nervous System Neoplasms in Children [PDF]
Central nervous system (CNS) neoplasms are the second most common childhood malignancy after leukemia and the most common solid organ neoplasm in children. Diagnostic dilemmas with small specimens from CNS neoplasms are often the result of multifactorial
Na Rae Kim, Sung-Hye Park
doaj +2 more sources
THE MAIN DIRECTIONS FOR PHARMACOLOGICAL CORRECTION (COMBINATIONS OF DRUGS FOR GENERAL ANESTHESIA) OF NEUROLOGICAL AND COGNITIVE DISORDERS IN PATIENTS WITH NEOPLASMS OF THE CENTRAL NERVOUS SYSTEM [PDF]
Introduction: the problem of neuroprotective or neurodegenerative effects of drugs for general anesthesia is relevant in connection with a large number of cases of postoperative cognitive dysfunction (POCD).
Andrey Kolesnikov +5 more
doaj +7 more sources
Intraoperative Frozen Cytology of Central Nervous System Neoplasms: An Ancillary Tool for Frozen Diagnosis [PDF]
Background Pathologic diagnosis of central nervous system (CNS) neoplasms is made by comparing light microscopic, immunohistochemical, and molecular cytogenetic findings with clinicoradiologic observations.
Myunghee Kang +18 more
doaj +2 more sources
Primary central nervous system neoplasms in African hedgehogs [PDF]
In this retrospective study, we describe the clinicopathologic and immunohistochemical findings in a series of primary central nervous system (CNS) neoplasms in African hedgehogs ( Atelerix albiventris). Twelve CNS neoplasms were found among 762 African hedgehog submissions (1.6%) to a private diagnostic laboratory in an 18-y period. The median age of
Juan F, Muñoz-Gutiérrez +2 more
openaire +3 more sources
Meningiomas occurring during long-term survival after treatment for childhood cancer
Childhood cancer is rare but improvements in treatment over the past five decades have resulted in a cohort of more than 30,000 long-term survivors of childhood cancer in the UK with more added annually.
Elaine Sugden +4 more
doaj +2 more sources
Immunohistochemical Study of Ki-67 Labelling Index in Neoplasms of Central Nervous System [PDF]
Introduction: The central nervous system tumours show a varied histopathological spectrum. The cell proliferation index may provide an objective method for assessing tumour biology. The Ki-67 is considered to be the most reliable proliferative marker
Anuradha G Patil +3 more
doaj +1 more source
Mast cells in central nervous system neoplasms: an immunohistochemical study
Objective: To investigate the relationship between mast cells (MCs) and different central nervous system (CNS) tumors. Methods: It was a comparative immunohistochemical study to investigate the presence, number, and location of MCs in pilocytic ...
Aldair Ochoa-Rojas +6 more
doaj +1 more source
Radiotherapy in Current Neuro-Oncology: There Is Still Much to Reveal
Radiation therapy (RT) has a pivotal role in the treatment of Central Nervous System (CNS) neoplasms and is routinely employed for both benign and malignant lesions [...]
Gianluca Ferini +1 more
doaj +1 more source
Not all roses are sweet—Pediatric ependymoma
Ependymomas are rare malignant neoplasms that originate from radial glial cells within the central nervous system. Within pediatric central nervous tumors, ependymomas constitute the third most common entity with the majority occurring within the ...
George V. Koshy +2 more
doaj +1 more source

