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An Uncommon Case of Disseminated Human Herpesvirus 6 Infection in an Immunocompetent Adult. [PDF]
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NEURAL ROUTE OF INFECTION IN VIRAL DISEASES OF THE CENTRAL NERVOUS SYSTEM
The Lancet, 1974Abstract Experimental evidence has accumulated that axon terminals, particularly motor end-plates, are capable of endocytosis, and that tracer substances taken up at or near presynaptic sites can be transported along the axons in a retrograde direction up to the perikaryonal region of the parent cells.
K, Blinzinger, A P, Anzil
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Journal of the Neurological Sciences, 1994 The intrathecal synthesis of interleukin 10 (IL-10) was investigated in 120 paired cerebrospinal fluid (CSF) and serum specimens from patients with various inflammatory and non-inflammatory diseases of the central nervous system (CNS). IL-10 was not demonstrated in the sera, but detectable levels were found in the CSF from: patients with acute viral ...
GALLO, PAOLO +6 more
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Viral Diseases of the Central Nervous System
Topics in Magnetic Resonance Imaging, 2005Viral diseases of the central nervous system encompass a wide range of different processes, mainly inflammation affecting the brain (encephalitis), the meninges (meningitis), or a combined meningoencephalitis. The spinal cord can be affected as well (myelitis).
Claudia, Leite +2 more
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VIRAL DISEASE OF THE CENTRAL NERVOUS SYSTEM
Journal of the American Medical Association, 1959Viral studies were made of 1,407 patients with clinical manifestations of infectious disease involving the central nervous system. Both virus isolation and serologic methods were used. The results showed apparent differences in the etiology of clinical poliomyelitis and aseptic meningitis which correlated with the degree of prior immunization with ...
E H, LENNETTE +3 more
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The process dynamics of viral and bacterial diseases of the central nervous system
Journal of the Neurological Sciences, 1980Several patients with herpes simplex encephalitis developed a prolonged humoral immune reaction within the central nervous system, which was evaluated by the measurement of locally synthesized immunoglobulin fractions in cerebrospinal fluid. Such phasic immune responses seem to occur predominantly in CNS infections with herpes and myxo/paramyxo viruses.
K, Felgenhauer, R, Ackermann, G, Schliep
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Some Viral Central Nervous System Diseases
A.M.A. Journal of Diseases of Children, 1959Introduction Since the isolation and classification of Coxsackie viruses of Group B by Dalldorf 1 numerous investigations concerning the etiologic role of these agents as the cause of aseptic meningitis have been carried out both in the United States and abroad.
N, KHOOBYARIAN +4 more
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Viral Gene Therapy for Central Nervous System Diseases
2008From a theoretical proposal in 1980’s, gene therapy involving the use of viral vectors to deliver genes for medical treatment of disease has come a long way. Given the complexity and the blood-brain barrier, delivery to the central nervous system (CNS), and the efficacy thereof on brain diseases has been an enormous challenge for gene therapies and ...
Pedro R. Lowenstein +2 more
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Viral Central Nervous System Disease
JAMA, 1962Virologic studies were done on 511 patients with suspected viral disease of the central nervous system. In 368 cases of aseptic meningitis, infections were encountered with a total of 20 different enteroviruses (of which Coxsackie B5 was the most frequent) and with the mumps and herpes simplex viruses.
E H, LENNETTE, R L, MAGOFFIN, E G, KNOUF
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