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Epstein-Barr Virus and Multiple Sclerosis: Mechanistic Insights into Virus-Driven Autoimmunity. [PDF]

Microorganisms
Bashiardes S, Krashias G, Englezou E, Lambrianides A, Pitsas G, Pantzaris M, Richter J.   +6 more
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NEURAL ROUTE OF INFECTION IN VIRAL DISEASES OF THE CENTRAL NERVOUS SYSTEM

Lancet, The, 1974
Abstract Experimental evidence has accumulated that axon terminals, particularly motor end-plates, are capable of endocytosis, and that tracer substances taken up at or near presynaptic sites can be transported along the axons in a retrograde direction up to the perikaryonal region of the parent cells.
K Blinzinger
exaly   +3 more sources

Viral Diseases of the Central Nervous System

Topics in Magnetic Resonance Imaging, 2005
Viral diseases of the central nervous system encompass a wide range of different processes, mainly inflammation affecting the brain (encephalitis), the meninges (meningitis), or a combined meningoencephalitis. The spinal cord can be affected as well (myelitis).
Claudia, Leite, Alcino, Barbosa, Leandro T, Lucato   +2 more
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VIRAL DISEASE OF THE CENTRAL NERVOUS SYSTEM

Journal of the American Medical Association, 1959
Viral studies were made of 1,407 patients with clinical manifestations of infectious disease involving the central nervous system. Both virus isolation and serologic methods were used. The results showed apparent differences in the etiology of clinical poliomyelitis and aseptic meningitis which correlated with the degree of prior immunization with ...
E H, LENNETTE, R L, MAGOFFIN, N J, SCHMIDT, A C, HOLLISTER   +3 more
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The process dynamics of viral and bacterial diseases of the central nervous system

Journal of the Neurological Sciences, 1980
Several patients with herpes simplex encephalitis developed a prolonged humoral immune reaction within the central nervous system, which was evaluated by the measurement of locally synthesized immunoglobulin fractions in cerebrospinal fluid. Such phasic immune responses seem to occur predominantly in CNS infections with herpes and myxo/paramyxo viruses.
K, Felgenhauer, R, Ackermann, G, Schliep
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Some Viral Central Nervous System Diseases

A.M.A. Journal of Diseases of Children, 1959
Introduction Since the isolation and classification of Coxsackie viruses of Group B by Dalldorf 1 numerous investigations concerning the etiologic role of these agents as the cause of aseptic meningitis have been carried out both in the United States and abroad.
N, KHOOBYARIAN, J, DRAPER, A C, DWYER, Y K, MURTHY, D N, WALCHER   +4 more
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Viral Gene Therapy for Central Nervous System Diseases

2008
From a theoretical proposal in 1980’s, gene therapy involving the use of viral vectors to deliver genes for medical treatment of disease has come a long way. Given the complexity and the blood-brain barrier, delivery to the central nervous system (CNS), and the efficacy thereof on brain diseases has been an enormous challenge for gene therapies and ...
Pedro R. Lowenstein, Kurt M. Kroeger, Maria G. Castro   +2 more
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Viral Central Nervous System Disease

JAMA, 1962
Virologic studies were done on 511 patients with suspected viral disease of the central nervous system. In 368 cases of aseptic meningitis, infections were encountered with a total of 20 different enteroviruses (of which Coxsackie B5 was the most frequent) and with the mumps and herpes simplex viruses.
E H, LENNETTE, R L, MAGOFFIN, E G, KNOUF
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Magnetic Resonance Imaging in Viral and Prion Diseases of the Central Nervous System

Topics in Magnetic Resonance Imaging, 2014
The early detection and specific diagnosis of viral infections of the central nervous system are important because many of these diseases are potentially treatable. However, clinical symptoms and physical examination are often nonspecific, and rapid diagnostic tests are available for some, but not all, viruses.
Behroze, Vachha, Rafael, Rojas, Sanjay P, Prabhu, Rafeeque, Bhadelia, Gul, Moonis   +4 more
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Autoimmune diseases of central nervous system and respiratory viral infections in children

S.S. Korsakov Journal of Neurology and Psychiatry
Foreign data about the role of influenza virus, measles and SARS-CoV-2 in the development of autoimmune diseases is described. The main characteristics of most frequent autoimmune diseases is given. The authors give characteristics of influenza virus, measles and SARS-CoV-2 virus as infectious agents- triggers of autoimmune central nervous system ...
N.V. Skripchenko, G.F. Zheleznikova, L.A. Alekseeva, T.V. Bessonova, P.S. Verbenko, E.Yu. Skripchenko   +5 more
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