Results 91 to 100 of about 726,644 (313)

Protective effect and mechanism of allicin on renal injury in rats with membranous nephropathy

open access: yesLinchuang shenzangbing zazhi
Objective To explore the effect of allicin on renal injury in rats with membranous nephropathy (MN) and elucidate its potential mechanism. Methods A total of 65 male Wistar rats were assigned into two groups of normal (n = 10) and modeling (n = 55 ...
Fei-fei Guan, Zhao-xu Han
doaj   +1 more source

Changing healthcare systems in Asia [PDF]

open access: yes, 2004
Outline of key changes in healthcare systems in Asia including company developments and trade union ...
Lethbridge, Jane
core  

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

New Zealand regions, 1986 – 2001: Hospitalisation and some related health facts [PDF]

open access: yes, 2006
Once age and gender composition is controlled for, regional health differentials are a function of problems of health service delivery, of socio-economic variance, and overall Māori Pakeha health differences.
Baxendine, Sandra   +3 more
core   +1 more source

Perspectives in educating molecular pathologists on liquid biopsy: Toward integrative, equitable, and decentralized precision oncology

open access: yesMolecular Oncology, EarlyView.
Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié   +13 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Beds for Boomers: Will California's Supply of Services Meet Senior Demand? [PDF]

open access: yes, 2015
California is home to the largest population of seniors in the country; in 2013, 4.8 million Californians, nearly 13% of the state's population, were age 65 and older.

core  

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

Improving precision instrument cleaning with a quality control module: implementation and outcomes

open access: yesFrontiers in Public Health
ObjectiveTo evaluate the effectiveness of a cleaning quality control module integrated into a hospital’s Disinfection Supply Center (DSC) for improving the cleaning quality of precision surgical instruments.MethodsIn June 2023, a cleaning quality control
Juan Xiong   +6 more
doaj   +1 more source

Pick-n-mix approaches to technology supply : XML as a standard “glue” linking universalised locals [PDF]

open access: yes, 2001
We report on our experiences in a participatory design project to develop ICTs in a hospital ward working with deliberate self-harm patients. This project involves the creation and constant re-creation of sociotechnical ensembles in which XML-related ...
Hartswood, Mark   +3 more
core  

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