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Brain sensory network activity underlies reduced nociceptive initiated and nociplastic pain via acupuncture in fibromyalgia. [PDF]
Sridhar A +7 more
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Central tolerance in T cells, what’s new?
Alex Jhonier Imbachí Salamanca +1 more
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Developing negative split pacing in endurance athletes: practical guidelines and training models. [PDF]
Grivas GV, Safari K, Hemmatinafar M.
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Monitoring enteral feeding tolerance in a critically ill patient using point-of-care ultrasound. [PDF]
Neves RPS, Assis AP, Russo CMC.
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2013
A critical function of the thymus is to help enforce tolerance to self. The importance of central tolerance in preventing autoimmunity has been enlightened by a deeper understanding of the interactions of developing T cells with a diverse population of thymic antigen presenting cell populations.
Maria L, Mouchess, Mark, Anderson
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A critical function of the thymus is to help enforce tolerance to self. The importance of central tolerance in preventing autoimmunity has been enlightened by a deeper understanding of the interactions of developing T cells with a diverse population of thymic antigen presenting cell populations.
Maria L, Mouchess, Mark, Anderson
openaire +2 more sources
A CENTRAL ROLE FOR CENTRAL TOLERANCE
Annual Review of Immunology, 2006Recent elucidation of the role of central tolerance in preventing organ-specific autoimmunity has changed our concepts of self/nonself discrimination. This paradigmatic shift is largely attributable to the discovery of promiscuous expression of tissue-restricted self-antigens (TRAs) by medullary thymic epithelial cells (mTECs).
Bruno, Kyewski, Ludger, Klein
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Central tolerance: good but imperfect
Immunological Reviews, 2006Summary: T‐cell development is a highly coordinated process that depends on interactions between thymocytes, thymic epithelium, and bone marrow (BM)‐derived dendritic cells (DCs). Before entering the peripheral T‐cell pool, thymocytes are subject to negative selection, a process that eliminates (or deletes) T cells with high affinity toward self ...
Alena M, Gallegos, Michael J, Bevan
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Tolerance to centrally administered phenobarbital
Biochemical Pharmacology, 1976Abstract Rats with permanent indwelling cerebral ventricular cannulae were shown to lose their righting reflex in response to centrally injected phenobarbital in a dose-related manner. Administration of four daily injections of 800 μg each over a 4- to 5-day period produced a gradual tolerance to the hypnotic effect, which was reversible after ...
M J, Mycek, H E, Brezenoff
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